Results 41 to 50 of about 543,335 (289)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Self-Calibration Method of Zooming Camera

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2016
In this article we proposed a novel approach to self- calibrate a camera with variable focal length. We show that the estimation of camera’s intrinsic parameters is possible from only two points of an unknown planar scene.
Ismail El Batteoui   +2 more
doaj   +1 more source

From the Basic Psychological Needs Satisfaction to Intrinsic Motivation: Mediating Effect of Academic Integration

open access: yesFrontiers in Psychology, 2021
The studies show a positive and direct relationship between basic psychological needs satisfaction and intrinsic motivation of the students. However, there is a lack of studies that analyze the psychological processes that affect these relationships. For
Jorge Vergara-Morales, Milenko Del Valle
doaj   +1 more source

Non-perturbative bottom PDF and its possible impact on new physics searches

open access: yes, 2015
Heavy quark parton distribution functions (PDFs) play an important role in several Standard Model and New Physics processes. Most PDF analyses rely on the assumption that the charm and bottom PDFs are generated perturbatively by gluon splitting and do ...
Kusina, A.
core   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Involution and Constrained Dynamics I: The Dirac Approach

open access: yes, 1995
We study the theory of systems with constraints from the point of view of the formal theory of partial differential equations. For finite-dimensional systems we show that the Dirac algorithm completes the equations of motion to an involutive system.
Courant R   +30 more
core   +3 more sources

Mathisson-Papapetrou equations in metric and gauge theories of gravity in a Lagrangian formulation [PDF]

open access: yes, 2005
We present a simple method to derive the semiclassical equations of motion for a spinning particle in a gravitational field. We investigate the cases of classical, rotating particles (pole-dipole particles), as well as particles with intrinsic spin.
Balasin H   +22 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Dynamic Instability of Beams Under Tip Follower Forces Using Geometrically Exact, Fully Intrinsic Equations

open access: yesLatin American Journal of Solids and Structures
In this study, the dynamic instability of beams under tip follower forces are considered. The beam is modeled by using the geometrically exact, fully intrinsic beam equations which is subjected to an inclined tip follower force.
Mohammadreza Amoozgar, Hossein Shahverdi
doaj   +1 more source

Determination of the Position Vectors of Curves from Intrinsic Equations in G3

open access: yesWalailak Journal of Science and Technology, 2014
In this paper, we investigate the position vectors of the curves and the general helices in Galilean space G3. We find the differential equations for the position vectors of such curves.
Handan ÖZTEKIN, Serpil TATLIPINAR
doaj   +1 more source

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