Results 51 to 60 of about 90,190 (300)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Asymptotic justification of the intrinsic equations of Koiter's model of a linearly elastic shell [PDF]

open access: yes, 2019
International audienceWe show that the intrinsic equations of Koiter's model of a linearly elastic shell can be derived from the intrinsic formulation of the three-dimensional equations of a linearly elastic shell, by using an appropriate a priori ...
Cristinel Mardare   +4 more
core   +1 more source

Intrinsic Bi-Stability Due to Local Dipole–Dipole Interactions in Two-Level Systems and in Excited Crystalline Atomic Dimers

open access: yesSolids
Intrinsic optical bi-stability in dense two-level systems is developed for the bad cavity limit where electromagnetic modes are adiabatically eliminated. Each atom interacts via dipole–dipole forces with its nearby spatial distribution of atoms.
Yacob Ben-Aryeh
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Chemical master versus chemical langevin for first-order reaction networks [PDF]

open access: yes, 2008
Markov jump processes are widely used to model interacting species in circumstances where discreteness and stochasticity are relevant. Such models have been particularly successful in computational cell biology, and in this case, the interactions are ...
Higham, Desmond J., Khanin, Raya
core   +1 more source

Geometrically Nonlinear Analysis of Composite Beams Based Using a Space–Time Finite Element Method

open access: yesAerospace
In this paper, we present a transient-format time-continuous Galerkin finite element method for fully intrinsic geometrically exact beam equations that are energy-consistent.
Xin Hu, Lidao Chen, Yong Liu
doaj   +1 more source

Generalization of a Double-Point Method to Determine the Intrinsic Viscosity in a Polymer-Solvent Mixture

open access: yesChemical Engineering Transactions, 2013
A double-point method proposed in literature for the determination of the Intrinsic Viscosity of a polymer-solvent solution and based on the Ram-Moham-Rao single point equation, have been extended to all single-point expressions available in literature ...
E.A. Diez   +4 more
doaj   +1 more source

Rolling Stiefel Manifolds Equipped with α-Metrics

open access: yesMathematics, 2023
We discuss the rolling, without slipping and without twisting, of Stiefel manifolds equipped with α-metrics, from an intrinsic and an extrinsic point of view.
Markus Schlarb   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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