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The Thermodynamic Basis of the Fuzzy Interaction of an Intrinsically Disordered Protein

Angewandte Chemie - International Edition, 2017
San Hadži   +2 more
exaly  

Analysis of Missense Tolerance (MTR) and Constrained Coding Regions (CCR) in pathological conditions-related Intrinsically Disordered Proteins (IDPs).

Genetic constraint is the depletion of disruptive variation caused by purifying natural selection. Coding regions in the genome with these characteristics can be implied to have an essential function or be involved in disease pathology. This project explores the intersection of genetically constrained regions and Intrinsically Disordered Regions (IDRs)
openaire   +1 more source

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