Results 171 to 180 of about 23,171 (195)

[Intrinsically disordered proteins (IDPs) and the impact on cell stress resistance].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2022
Intrinsically disordered proteins (IDPs) are proteins or protein regions that fail to get folded into definite three-dimensional structures but participate in various biological processes and perform specific functions. Defying the traditional protein "sequence-structure-function" paradigm, they enrich the protein "structure-function" diversity ...
Ning, Yan, Hongxing, Li, Longhao, Wu, Shuo, Yang, Lujiang, Hao, Xiaoming, Bao   +5 more
openaire   +1 more source

Machine Learning Subtle Conformational Change due to Phosphorylation in Intrinsically Disordered Proteins.

Journal of Physical Chemistry B, 2023
Phosphorylation of intrinsically disordered proteins/regions (IDPs/IDRs) has a profound effect in biological functions such as cell signaling, protein folding or unfolding, and long-range allosteric effects.
Subinoy Adhikari, Jagannath Mondal
semanticscholar   +1 more source

Longitudinal Relaxation Properties of 1HN and 1Hα Determined by Direct-Detected 13C NMR Experiments to Study Intrinsically Disordered Proteins (IDPs)

Journal of Magnetic Resonance, 2015
Intrinsically disordered proteins (IDPs) are functional proteins containing large fragments characterized by high local mobility. Bioinformatic studies have suggested that a significant fraction (more than 30%) of eukaryotic proteins has disordered regions of more than 50 amino acids in length.
Bernhard Brutscher, Roberta Pierattelli, Tomáš Hošek   +2 more
exaly   +4 more sources

Molecular Bases of Salinity Resistance via Intrinsic Disordered Protein (IDP)

2023
Salt-affected soil is a prominent challenge in agriculture. Nowadays, more than 800 million hectares of land (about 6% of the world’s total land area) are induced with high salt concentrations, and thus, are unsuitable for growing typically salt-sensitive crop plants. The ongoing salinization of arable land exacerbates this limitation.
openaire   +2 more sources

IDP-EDL: Enhancing Intrinsically Disordered Protein Prediction by Combining Protein Language Model and Ensemble Deep Learning

Briefings in Bioinformatics
Abstract Identification of intrinsically disordered regions (IDRs) in proteins is essential for understanding fundamental cellular processes. The IDRs can be divided into long disordered regions (LDRs) and short disordered regions (SDRs) according to their lengths.
Hang Wei, Xiaopeng Jin, Saisai Sun
exaly   +3 more sources

A multi-responsive intrinsically disordered protein (IDP)-directed green synthesis of fluorescent gold nanoclusters

Journal of Materials Chemistry B, 2015
Herein we demonstrate the green synthesis of fluorescent gold nanoclusters (AuNCs) using a multi-responsive intrinsically disordered protein (IDP) polymer, Rec1-resilin, as a multi-functional template.
Balu, R., Bourgeois, L., Elvin, C., Hill, A., Choudhury, N., Dutta, N.   +5 more
openaire   +5 more sources

The gene expression profiling of hepatocellular carcinoma by a network analysis approach shows a dominance of intrinsically disordered proteins (IDPs) between hub nodes

Molecular BioSystems, 2015
Abstract We have analyzed the transcriptomic data from patients with hepatocellular carcinoma (HCC) after viral HCV infection at the various stages of the disease by means of a networking analysis using the publicly available E-MTAB-950 dataset.
Singh S, Colonna G, DI BERNARDO, Giovanni, Bergantino F, CAMMAROTA, Marcella, Castello G, Costantini S.   +6 more
openaire   +2 more sources

IDP-T5CKNN: Protein Language Models for Prediction of Intrinsically Disordered Proteins

Current Computer Science
Introduction: Disordered proteins (IDPs) and disordered protein regions (IDRs) have important roles in cellular signalling and regulation and in disease development. However, their flexible conformations create challenges in annotating them through computational methods.
openaire   +1 more source

Intrinsically Disordered Proteins (IDPs)

2022
openaire   +1 more source

RFPR-IDP: Reduce the False Positive Rates for Intrinsically Disordered Protein and Region Prediction by Incorporating Both Fully Ordered Proteins and Disordered Proteins

Briefings in Bioinformatics, 2021
Xiaolong Wang, Liu Yumeng
exaly