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Genetic constraint is the depletion of disruptive variation caused by purifying natural selection. Coding regions in the genome with these characteristics can be implied to have an essential function or be involved in disease pathology. This project explores the intersection of genetically constrained regions and Intrinsically Disordered Regions (IDRs)
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Homocysteinylation of intrinsically disordered proteins (IDP) and their tranformations.
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