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Introns increase gene expression in Caenorhabditis elegans by a mechanism that must be at least partly different than in plants [PDF]
Scientific ReportsThe wide diversity of organisms in which introns stimulate gene expression suggests that this is an ancient phenomenon. However, the mechanisms through which introns boost expression remain poorly understood, and the degree the which the action of ...
Alan B. Rose +5 more
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Frontiers in Microbiology, 2023 IntroductionMitochondria are essential organelles in the eukaryotic cells and responsible for the energy production but are also involved in many other functions including virulence of some fungal species.
Kajsa Himmelstrand +4 more
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Splice and Dice: Intronic microRNAs, Splicing and Cancer
Biomedicines, 2021 Introns span only a quarter of the human genome, yet they host around 60% of all known microRNAs. Emerging evidence indicates the adaptive advantage of microRNAs residing within introns is attributed to their complex co-regulation with transcription and ...
Alex C. H. Wong, John E. J. Rasko
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The position of the longest intron is related to biological functions in some human genes
Frontiers in Genetics, 2023 The evidence that introns can influence different levels of transfer of genetic information between DNA and the final product is increasing. Longer first introns were found to be a general property of eukaryotic gene structure and shown to contain a ...
Pavel Dvorak +5 more
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Polymorphisms of mbl gene introns and their association with mbl serum levels in hu sheep [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 PCR single-strand conformation polymorphism (SSCP) and DNA sequencing techniques were used to analyze the genetic polymorphism of mannose-binding lectin (MBL) gene 3 introns in Hu sheep.
Mengting ZHAI +6 more
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Can Introns Stabilize Gene Duplication?
Biology, 2022 Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to
Gioacchino Micheli, Giorgio Camilloni
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Dynamics of genomic innovation in the unicellular ancestry of animals
eLife, 2017 Which genomic innovations underpinned the origin of multicellular animals is still an open debate. Here, we investigate this question by reconstructing the genome architecture and gene family diversity of ancestral premetazoans, aiming to date the ...
Xavier Grau-Bové +6 more
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Agronomy, 2023 Amino acid transporters (AATs) play a crucial role in facilitating the movement of amino acids across cellular membranes, which is vital for the growth and development of plants.
Itishree Nayak +13 more
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Defining the location of promoter-associated R-loops at near-nucleotide resolution using bisDRIP-seq
eLife, 2017 R-loops are features of chromatin consisting of a strand of DNA hybridized to RNA, as well as the expelled complementary DNA strand. R-loops are enriched at promoters where they have recently been shown to have important roles in modifying gene ...
Jason G Dumelie, Samie R Jaffrey
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Exploring the Relationship between Fusion Genes and MicroRNAs in Cancer
Cells, 2023 Fusion genes are key cancer driver genes that can be used as potential drug targets in precision therapies, and they can also serve as accurate diagnostic and prognostic biomarkers.
Saurav Panicker +4 more
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