Results 1 to 10 of about 137,846 (269)

The position of the longest intron is related to biological functions in some human genes

open access: yesFrontiers in Genetics, 2023
The evidence that introns can influence different levels of transfer of genetic information between DNA and the final product is increasing. Longer first introns were found to be a general property of eukaryotic gene structure and shown to contain a ...
Pavel Dvorak   +5 more
doaj   +1 more source

Polymorphisms of mbl gene introns and their association with mbl serum levels in hu sheep [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2019
PCR single-strand conformation polymorphism (SSCP) and DNA sequencing techniques were used to analyze the genetic polymorphism of mannose-binding lectin (MBL) gene 3 introns in Hu sheep.
Mengting ZHAI   +6 more
doaj   +1 more source

Multiple rearrangements and low inter- and intra-species mitogenome sequence variation in the Heterobasidion annosum s.l. species complex

open access: yesFrontiers in Microbiology, 2023
IntroductionMitochondria are essential organelles in the eukaryotic cells and responsible for the energy production but are also involved in many other functions including virulence of some fungal species.
Kajsa Himmelstrand   +4 more
doaj   +1 more source

Animal, Fungi, and Plant Genome Sequences Harbor Different Non-Canonical Splice Sites

open access: yesCells, 2020
Most protein-encoding genes in eukaryotes contain introns, which are interwoven with exons. Introns need to be removed from initial transcripts in order to generate the final messenger RNA (mRNA), which can be translated into an amino acid sequence ...
Katharina Frey, Boas Pucker
doaj   +1 more source

Splice and Dice: Intronic microRNAs, Splicing and Cancer

open access: yesBiomedicines, 2021
Introns span only a quarter of the human genome, yet they host around 60% of all known microRNAs. Emerging evidence indicates the adaptive advantage of microRNAs residing within introns is attributed to their complex co-regulation with transcription and ...
Alex C. H. Wong, John E. J. Rasko
doaj   +1 more source

Can Introns Stabilize Gene Duplication?

open access: yesBiology, 2022
Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to
Gioacchino Micheli, Giorgio Camilloni
doaj   +1 more source

Exploring the Relationship between Fusion Genes and MicroRNAs in Cancer

open access: yesCells, 2023
Fusion genes are key cancer driver genes that can be used as potential drug targets in precision therapies, and they can also serve as accurate diagnostic and prognostic biomarkers.
Saurav Panicker   +4 more
doaj   +1 more source

Genome-Wide Analysis of Amino Acid Transporter Gene Family Revealed That the Allele Unique to the Aus Variety Is Associated with Amino Acid Permease 17 (OsAAP17) Amplifies Both the Tiller Count and Yield in Indica Rice (Oryza sativa L.)

open access: yesAgronomy, 2023
Amino acid transporters (AATs) play a crucial role in facilitating the movement of amino acids across cellular membranes, which is vital for the growth and development of plants.
Itishree Nayak   +13 more
doaj   +1 more source

ChloroSeq, an Optimized Chloroplast RNA-Seq Bioinformatic Pipeline, Reveals Remodeling of the Organellar Transcriptome Under Heat Stress

open access: yesG3: Genes, Genomes, Genetics, 2016
Although RNA-Seq has revolutionized transcript analysis, organellar transcriptomes are rarely assessed even when present in published datasets. Here, we describe the development and application of a rapid and convenient method, ChloroSeq, to delineate ...
Benoît Castandet   +3 more
doaj   +1 more source

Mitochondrial genome annotation with MFannot: a critical analysis of gene identification and gene model prediction

open access: yesFrontiers in Plant Science, 2023
Compared to nuclear genomes, mitochondrial genomes (mitogenomes) are small and usually code for only a few dozen genes. Still, identifying genes and their structure can be challenging and time-consuming.
B. Franz Lang   +5 more
doaj   +1 more source

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