Results 21 to 30 of about 292,600 (397)

Exploring the Relationship between Fusion Genes and MicroRNAs in Cancer

open access: yesCells, 2023
Fusion genes are key cancer driver genes that can be used as potential drug targets in precision therapies, and they can also serve as accurate diagnostic and prognostic biomarkers.
Saurav Panicker   +4 more
doaj   +1 more source

Mitochondrial genome annotation with MFannot: a critical analysis of gene identification and gene model prediction

open access: yesFrontiers in Plant Science, 2023
Compared to nuclear genomes, mitochondrial genomes (mitogenomes) are small and usually code for only a few dozen genes. Still, identifying genes and their structure can be challenging and time-consuming.
B. Franz Lang   +5 more
doaj   +1 more source

Can Introns Stabilize Gene Duplication?

open access: yesBiology, 2022
Gene duplication is considered one of the most important events that determine the evolution of genomes. However, the neo-duplication condition of a given gene is particularly unstable due to recombination events. Several mechanisms have been proposed to
Gioacchino Micheli, Giorgio Camilloni
doaj   +1 more source

Comparative analysis of the complete mitochondrial genomes of four cordyceps fungi

open access: yesEcology and Evolution, 2022
Cordyceps is a large group of entomogenous, medicinally important fungi. In this study, we sequenced, assembled, and annotated the entire mitochondrial genome of Ophiocordyceps xuefengensis, in addition to comparing it against other three complete ...
Can Zhong   +7 more
doaj   +1 more source

The position of the longest intron is related to biological functions in some human genes

open access: yesFrontiers in Genetics, 2023
The evidence that introns can influence different levels of transfer of genetic information between DNA and the final product is increasing. Longer first introns were found to be a general property of eukaryotic gene structure and shown to contain a ...
Pavel Dvorak   +5 more
doaj   +1 more source

Horizontal Transfer and Gene Loss Shaped the Evolution of Alpha-Amylases in Bilaterians

open access: yesG3: Genes, Genomes, Genetics, 2020
The subfamily GH13_1 of alpha-amylases is typical of Fungi, but it is also found in some unicellular eukaryotes (e.g., Amoebozoa, choanoflagellates) and non-bilaterian Metazoa.
Andrea Desiderato   +3 more
doaj   +1 more source

Comprehensive database and evolutionary dynamics of U12-type introns

open access: yesNucleic Acids Research, 2020
During nuclear maturation of most eukaryotic pre-messenger RNAs and long non-coding RNAs, introns are removed through the process of RNA splicing. Different classes of introns are excised by the U2-type or the U12-type spliceosomes, large complexes of ...
Devlin C. Moyer   +4 more
semanticscholar   +1 more source

Polymorphisms of mbl gene introns and their association with mbl serum levels in hu sheep [PDF]

open access: yesKafkas Universitesi Veteriner Fakültesi Dergisi, 2019
PCR single-strand conformation polymorphism (SSCP) and DNA sequencing techniques were used to analyze the genetic polymorphism of mannose-binding lectin (MBL) gene 3 introns in Hu sheep.
Mengting ZHAI   +6 more
doaj   +1 more source

Multiple rearrangements and low inter- and intra-species mitogenome sequence variation in the Heterobasidion annosum s.l. species complex

open access: yesFrontiers in Microbiology, 2023
IntroductionMitochondria are essential organelles in the eukaryotic cells and responsible for the energy production but are also involved in many other functions including virulence of some fungal species.
Kajsa Himmelstrand   +4 more
doaj   +1 more source

Identification of an Exceptionally Long Intron in the HAC1 Gene of Candida parapsilosis

open access: yesmSphere, 2018
The unfolded protein response (UPR) in the endoplasmic reticulum (ER) is well conserved in eukaryotes from metazoa to yeast. The transcription factor HAC1 is a major regulator of the UPR in many eukaryotes. Deleting HAC1 in the yeast Candida parapsilosis
Elise Iracane   +4 more
doaj   +1 more source

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