Results 91 to 100 of about 69,499 (257)

In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver [PDF]

, 2011
Cytochrome P450 (CYP) enzymes are widely studied for their involvement in metabolism of drugs and endogenous compounds. In porcine liver, CYP1A2,2Aand 2E1 are important for the metabolism of skatole.Feeding chicory roots to pigs is known to decrease the ...
Ekstrand, Bo, Rasmussen, Martin Krøyer, Zamaratskaia, Galia   +2 more
core   +1 more source

Correlation Between Gut Microbiota, Metabolites, and Diabetic Complications: A Two‐Sample Mendelian Randomization Study

Medicine Advances, EarlyView.
Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang, Leilei Zhai, Chan Huang, Liqin Li, Yong Wang, Jiaojiao Fan, Wei Zhou   +6 more
wiley   +1 more source

Inulin extracted from burdock root (Arctium lappa L.) incorporated alginate/chitosan hydrogel beads for probiotics encapsulation

Journal of Agriculture and Food Research
Burdock root is a reliable source of inulin, a prebiotic with potential benefits for probiotic encapsulation. This study aimed to extract inulin from burdock roots and assess its physicochemical properties and functional groups in comparison to standard ...
Korlid Thinkohkaew, Nichapa Aumphaiphensiri, Thakorn Tangamornsiri, Nuttawee Niamsiri, Pranut Potiyaraj, Inthawoot Suppavorasatit   +5 more
doaj   +1 more source

Postnatal maturation of the glomerular filtration rate in conventional growing piglets as potential juvenile animal model for preclinical pharmaceutical research [PDF]

, 2017
Adequate animal models are required to study the preclinical pharmacokinetics (PK), pharmacodynamics (PD) and safety of drugs in the pediatric subpopulation.
Croubels, Siska, Delanghe, Joris, Devreese, Mathias, Gasthuys, Elke, Heyndrickx, Marjolein, Millecam, Joske, Sys, Stanislas, Vande Walle, Johan, Vanderperren, Katrien   +8 more
core   +3 more sources

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]

, 2019
Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L., Johnson, David W., McFarlane, Catherine, Ramos, Christiane I.   +3 more
core   +1 more source

Review of nutrition management of pediatric intestinal pseudo‐obstruction

Nutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman, Raisa Rani James, Bushra El‐Amaireh, Andrea Adler, Kadakkal Radhakrishnan, Sujithra Velayuthan   +5 more
wiley   +1 more source

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E., Metzler-Zebeli, B.U., Mosenthin, R., Verstegen, M.W.A.   +3 more
core   +1 more source

Integrating indigenous crops in agroforestry systems: Lesser yam and teak mixed systems are more profitable than monocultures in Indonesia

PLANTS, PEOPLE, PLANET, EarlyView.
Major staple crops are often introduced and cultivated in monocultures. Yams are staple crops native to the majority of low‐ and middle‐income countries and can provide an alternative to introduced staple crops. We showed that lesser yams cultivated together with teak trees (planted at the border of the farm) are more profitable than lesser yam ...
Budiadi, Sawitri, Enggal Primananda, Aqmal Nur Jihad, Marco Campera, Rika Bela Rahmawati   +5 more
wiley   +1 more source

LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease. [PDF]

, 2019
The low-density lipoprotein receptor-related protein-1 (LRP1) has a dual role in the metabolism of the amyloid precursor protein (APP). In cellular models, LRP1 enhances amyloid-β (Aβ) generation via APP internalization and thus its amyloidogenic ...
Gordts, Philip LSM, Lechat, Benoit, Pietrzik, Claus U, Pradier, Laurent, Reekmans, Sara M, Roebroek, Anton JM, Storck, Steffen E, Van Gool, Bart   +7 more
core   +3 more sources