Results 61 to 70 of about 546,512 (289)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

An approach to exact solutions of the time-dependent supersymmetric two-level three-photon Jaynes-Cummings model

, 2003
By utilizing the property of the supersymmetric structure in the two-level multiphoton Jaynes-Cummings model, an invariant is constructed in terms of the supersymmetric generators by working in the sub-Hilbert-space corresponding to a particular ...
Alexanian M., Berry M. V., Berry M. V., Eberly J. H., Fu J., Gao X. C., Gao X. C., Gao X. C., Gao X. C., Imamolglu A., Jaynes E. T., Kien F. L., Lewis H., Lu H. X., Lu H. X., Mizrahi S. S., Shapere A., Shen J. Q., Simon B., Singh S., Sukumar C. V., Wei J., Wodkiewicz K., Wu Y.   +23 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Causal geometries and third-order ordinary differential equations [PDF]

, 2009
We discuss contact invariant structures on the space of solutions of a third-order ordinary differential equation. Associated to any third-order differential equation modulo contact transformations, Chern introduced a degenerate conformal Lorentzian ...
Holland, Jonathan, Sparling, George
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Symmetry Classification and Exact Solutions of a Variable Coefficient Space-Time Fractional Potential Burgers’ Equation

International Journal of Differential Equations, 2016
We investigate the symmetry properties of a variable coefficient space-time fractional potential Burgers’ equation. Fractional Lie symmetries and corresponding infinitesimal generators are obtained.
Manoj Gaur, K. Singh
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Ancient solutions of the homogenous Ricci flow on flag manifolds

Extracta Mathematicae, 2021
For any flag manifold M=G/K of a compact simple Lie group G we describe non-collapsing ancient invariant solutions of the homogeneous unnormalized Ricci flow.
S. Anastassiou, I. Chrysikos
doaj  

Scale-Invariant Rotating Black Holes in Quadratic Gravity

Entropy, 2015
Black hole solutions in pure quadratic theories of gravity are interesting since they allow the formulation of a set of scale-invariant thermodynamics laws.
Guido Cognola, Massimiliano Rinaldi, Luciano Vanzo   +2 more
doaj   +1 more source