Results 71 to 80 of about 3,164,214 (296)
Invariant Subspaces and Exact Solutions for Nonlinear Variable-Coefficient Beam-Type Equations
This paper investigates a class of generalized nonlinear variable-coefficient beam-type evolution equations motivated by the modeling of nonhomogeneous elastic structures with nonlinear effects.
Manal Badgaish
doaj +1 more source
Continuing invariant solutions towards the turbulent flow [PDF]
A new mathematical framework is proposed for characterizing the coherent motion of fluctuations around a mean turbulent channel flow. We search for statistically invariant coherent solutions of the unsteady Reynolds-averaged Navier–Stokes equations ...
PARENTE, Enza +14 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Some new invariant solutions of nonlinear fifth order partial differential equation via Lie approach
In this paper, the classical Lie symmetry analysis of (1+3) dimensional perturbed Zakharov–Kuznetsov (pZK) equation has been studied. We present a thorough classification of Lie point symmetries for pZK equation.
Muhammad Irshad +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Invariant solutions of the Cahn–Hilliard fluid
Lie group analysis classifies differential equations based on their dependence on arbitrary functions, thereby facilitating the generation of invariant solutions that are exact solutions.
Supaporn Suksern +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
INVARIANT FUNDAMENTAL SOLUTION OF THE WAVE OPERATOR
We present a method for determining a fundamental solution of the wave operator \(\square_ n=\partial^ 2/\partial t^ 2- \sum^{n}_{j=1}\partial^ 2/\partial x^ 2_ j\) for an arbitrary \(n\geq 1\) which, as we think, is simpler than other methods used up to now.
Szmydt, Zofia, Ziemian, Bogdan
openaire +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source

