Results 71 to 80 of about 3,164,214 (296)

Invariant Subspaces and Exact Solutions for Nonlinear Variable-Coefficient Beam-Type Equations

open access: yesMathematics
This paper investigates a class of generalized nonlinear variable-coefficient beam-type evolution equations motivated by the modeling of nonhomogeneous elastic structures with nonlinear effects.
Manal Badgaish
doaj   +1 more source

Continuing invariant solutions towards the turbulent flow [PDF]

open access: yes, 2022
A new mathematical framework is proposed for characterizing the coherent motion of fluctuations around a mean turbulent channel flow. We search for statistically invariant coherent solutions of the unsteady Reynolds-averaged Navier–Stokes equations ...
PARENTE, Enza   +14 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Some new invariant solutions of nonlinear fifth order partial differential equation via Lie approach

open access: yesPartial Differential Equations in Applied Mathematics
In this paper, the classical Lie symmetry analysis of (1+3) dimensional perturbed Zakharov–Kuznetsov (pZK) equation has been studied. We present a thorough classification of Lie point symmetries for pZK equation.
Muhammad Irshad   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Invariant solutions of the Cahn–Hilliard fluid

open access: yesExamples and Counterexamples
Lie group analysis classifies differential equations based on their dependence on arbitrary functions, thereby facilitating the generation of invariant solutions that are exact solutions.
Supaporn Suksern   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

INVARIANT FUNDAMENTAL SOLUTION OF THE WAVE OPERATOR

open access: yesDemonstratio Mathematica, 1986
We present a method for determining a fundamental solution of the wave operator \(\square_ n=\partial^ 2/\partial t^ 2- \sum^{n}_{j=1}\partial^ 2/\partial x^ 2_ j\) for an arbitrary \(n\geq 1\) which, as we think, is simpler than other methods used up to now.
Szmydt, Zofia, Ziemian, Bogdan
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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