Results 71 to 80 of about 546,512 (289)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gregory-Laflamme and superradiance encounter black resonator strings

open access: yesJournal of High Energy Physics, 2023
We construct novel black strings that are neither time-translation invariant, nor axisymmetric, nor translationally invariant in the string direction, but nevertheless have a helical Killing vector field.
Óscar J. C. Dias   +4 more
doaj   +1 more source

Infrared Behaviour and Running Couplings in Interpolating Gauges in QCD

open access: yes, 2005
We consider the class of gauges that interpolates between Landau- and Coulomb-gauge QCD, and show the non-renormalisation of the two independent ghost-gluon vertices.
A. Cucchieri   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The invariant subspace method for solving nonlinear fractional partial differential equations with generalized fractional derivatives

open access: yesAdvances in Difference Equations, 2020
In this paper, we show that the invariant subspace method can be successfully utilized to get exact solutions for nonlinear fractional partial differential equations with generalized fractional derivatives. Using the invariant subspace method, some exact
Mohamed S. Abdel Latif   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Topology of the gauge-invariant gauge field in two-color QCD

open access: yes, 1999
We investigate solutions to a nonlinear integral equation which has a central role in implementing the non-Abelian Gauss's Law and in constructing gauge-invariant quark and gluon fields. Here we concern ourselves with solutions to this same equation that
E. Coddington   +16 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Lie group analysis and its invariants for the class of multidimensional nonlinear wave equations

open access: yesNonlinear Analysis
We systematically classify Lie symmetries of a class of (2 + 1)-dimensional nonlinear wave equations. Our methodology proposes a symmetry classification for Lie generators applicable to four distinct cases inherent within this equation.
Akhtar Hussain   +3 more
doaj   +1 more source

A note on invariant subspaces and the solution of some classical functional equations [PDF]

open access: yes, 2013
We study the continuous solutions of several classical functional equations by using the properties of the spaces of continuous functions which are invariant under some elementary linear trans-formations.
Abu-Helaiel, Kh. F., Almira, J. M.
core  

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