Results 61 to 70 of about 1,911,169 (360)

Abundance, frequency and distribution pattern of tree species in recorded forest area of Western Himalaya

open access: yesNotulae Scientia Biologicae, 2020
The forest in India have a long history of human induced modifications through intensive forest management that began in the colonial period but continued afterwards to meet the wood-based demand until the forestry goals shifted towards conservation ...
Arun K. THAKUR   +2 more
doaj   +1 more source

The Relativity Concept Inventory: development, analysis and results [PDF]

open access: yesPhys. Rev. ST Physics Ed. Research 9, 010118 (2013), 2013
We report on a concept inventory for special relativity: the development process, data analysis methods, and results from an introductory relativity class. The Relativity Concept Inventory tests understanding of kinematic relativistic concepts. An unusual feature is confidence testing for each question.
arxiv   +1 more source

Inventory drivers in a pharmaceutical supply chain [PDF]

open access: yes, 2017
In recent years, inventory reduction has been a key objective of pharmaceutical companies, especially within cost optimization initiatives. Pharmaceutical supply chains are characterized by volatile and unpredictable demands –especially in emergent ...
Masvidal Andreu, Clara
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

The Maximization Inventory

open access: yesJudgment and Decision Making, 2012
AbstractWe present the Maximization Inventory, which consists of three separate scales: decision difficulty, alternative search, and satisficing. We show that the items of the Maximization Inventory have much better psychometric properties when compared to the original Maximization Scale (Schwartz et al., 2002).
Turner, Brandon M.   +3 more
openaire   +4 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Inventory of armourstone [PDF]

open access: yesE3S Web of Conferences, 2016
Natural armourstone is widely used for hydraulic works, both in the coastal domain and in border of rivers and torrents, especially to protect against flood and the effects of waves and currents. To meet the expectations associated with this resource, an inventory of armourstone quarries was realized on a national scale in France.
Valéry Le Turdu   +7 more
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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