Results 51 to 60 of about 692,259 (288)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Effect of bulk inversion asymmetry on the Datta-Das transistor

open access: yes, 2003
A model of the Datta-Das spin field-effect transistor is presented which, in addition to the Rashba interaction, takes into account the influence of bulk inversion asymmetry of zinc-blende semiconductors.
A. MacKinnon   +29 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A Model for TSUnami FLow INversion from Deposits (TSUFLIND)

open access: yes, 2015
Modern tsunami deposits are employed to estimate the overland flow characteristics of tsunamis. With the help of the overland-flow characteristics, the characteristics of the causative tsunami wave can be estimated.
Tang, Hui, Weiss, Robert
core   +1 more source

Groundwater-inverse-modeling

open access: yes, 2023
All the Python codes and data to reproduce the results of 'Groundwater inverse modeling: physics-informed neural network with separable constraints and errors'.
openaire   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Binary structure constrained gravity inversion based on seismic first arrival travel time data

open access: yesFrontiers in Earth Science, 2023
Gravity exploration method is one of the important methods for deep mineral resource exploration, but gravity data inversion has limited resolution ability in the vertical direction.
Xinhui Deng   +2 more
doaj   +1 more source

Theory of Fulde-Ferrell-Larkin-Ovchinnikov state of superconductors with and without inversion symmetry: Hubbard model approach

open access: yes, 2007
We study Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) state of superconductors with and without inversion symmetry based on the Hubbard model on the square lattice near half-filling, using the random phase approximation.
Adachi H.   +76 more
core   +1 more source

Spin Model for Inverse Melting and Inverse Glass Transition [PDF]

open access: yesPhysical Review Letters, 2004
A spin model that displays inverse melting and inverse glass transition is presented and analyzed. Strong degeneracy of the interacting states of an individual spin leads to entropic preference of the "ferromagnetic" phase, while lower energy associated with the non-interacting states yields a "paramagnetic" phase as temperature decreases.
Schupper, Nurith, Shnerb, Nadav M.
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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