Results 61 to 70 of about 692,259 (288)

Effects of image charges, interfacial charge discreteness, and surface roughness on the zeta potential of spherical electric double layers

open access: yes, 2012
We investigate the effects of image charges, interfacial charge discreteness, and surface roughness on spherical electric double layers in electrolyte solutions with divalent counter-ions in the setting of the primitive model.
Gouy G.   +8 more
core   +1 more source

Multiscale Modelling and Inverse Problems [PDF]

open access: yes, 2011
Submitted to the proceedings of the summer school "Numerical Analysis of Multiscale Problems", edited by I.G. Graham, T.Y. Hou, O. Lakkis and R. Scheichl.
Nolen, James   +2 more
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Coupling ecological concepts with an ocean-colour model: inversion modelling

open access: yesFrontiers in Remote Sensing
Monitoring phytoplankton from space can help detect shifts in marine ecosystems, particularly under accelerating climate change. However, most existing ocean-colour chlorophyll-a (Chl-a) algorithms are empirical in nature, and do not explicitly consider ...
Xuerong Sun   +18 more
doaj   +1 more source

Semi-empirical model of MOST and passive devices focused on narrowband RF blocks [PDF]

open access: yes, 2012
This paper presents a semi-empirical modeling of MOST and passive elements to be used in narrowband radiofrequency blocks for nanometer technologies. This model is based on a small set of look-up tables (LUTs) obtained via electrical simulations.
Fiorelli, Rafaella   +3 more
core  

Interaction induced edge states in HgTe/CdTe Quantum Well under magnetic field

open access: yes, 2019
In this paper, we study doped HgTe/CdTe quantum well with Hubbard-type interaction under perpendicular magnetic field using a lattice Bernevig-Hughes-Zhang (BHZ) model with a bulk inversion asymmetry (BIA) term.
Chen, Zewei, Ng, Tai Kai
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

MODEL SELECTION FOR SPECTROPOLARIMETRIC INVERSIONS [PDF]

open access: yesThe Astrophysical Journal, 2012
16 pages, 2 figures, 8 tables, accepted for publication in ...
Ramos, A. Asensio   +5 more
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

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