Evidence for active maintenance of inverted repeat structures identified by a comparative genomic approach. [PDF]
PLoS ONE, 2007 Inverted repeats have been found to occur in both prokaryotic and eukaryotic genomes. Usually they are short and some have important functions in various biological processes.
Guoyan Zhao +3 more
doaj +11 more sources
Inverted and mirror repeats in model nucleotide sequences [PDF]
Physical Review E, 2007 We analytically and numerically study the probabilistic properties of inverted and mirror repeats in model sequences of nucleic acids. We consider both perfect and non-perfect repeats, i.e. repeats with mismatches and gaps. The considered sequence models
Fabrizio Lillo +3 more
core +7 more sources
Identification of the transcriptional regulator NcrB in the nickel resistance determinant of Leptospirillum ferriphilum UBK03. [PDF]
PLoS ONE, 2011 The nickel resistance determinant ncrABCY was identified in Leptospirillum ferriphilum UBK03. Within this operon, ncrA and ncrC encode two membrane proteins that form an efflux system, and ncrB encodes NcrB, which belongs to an uncharacterized family ...
Tao Zhu +4 more
doaj +4 more sources
Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]
PLoS ONE, 2012 Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
doaj +6 more sources
Stability of an inverted repeat in a human fibrosarcoma cell [PDF]
Nucleic Acids Research, 1996 Deletions and rearrangements of DNA sequences within the genome of human cells result in mutations associated with human disease. We have developed a selection system involving a neo gene containing a DNA sequence inserted into the NcoI site that can be used to quantitatively assay deletion of this sequence from the chromosome. The spontaneous deletion
Phillip R. Kramer
openalex +5 more sources
Concentration of inverted repeats along human DNA
Journal of Integrative Bioinformatics, 2023 This work aims to describe the observed enrichment of inverted repeats in the human genome; and to identify and describe, with detailed length profiles, the regions with significant and relevant enriched occurrence of inverted repeats.
Bastos Carlos A. C. +3 more
doaj +4 more sources
Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification.
PLoS Genetics, 2015 DNA replication errors are a major driver of evolution--from single nucleotide polymorphisms to large-scale copy number variations (CNVs). Here we test a specific replication-based model to explain the generation of interstitial, inverted triplications ...
Bonita J Brewer +6 more
doaj +4 more sources
Crystallization of a Mos1 transposase-inverted-repeat DNA complex: biochemical and preliminary crystallographic analyses [PDF]
, 2007 A complex formed between Mos1 transposase and its inverted-repeat DNA has been crystallized. The crystals diffract to 3.25 Å resolution and exhibit monoclinic (P2(1)) symmetry, with unit-cell parameters a = 120.8, b = 85.1, c = 131.6 Å, β = 99.3°.
Finnegan, David J. +2 more
core +4 more sources
Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania [PDF]
, 2005 Attempts to inactivate an essential gene in the protozoan parasite Leishmania have often led to the generation of extra copies of the wild-type alleles of the gene.
Borst, Piet +5 more
core +5 more sources
Single tube, high throughput cloning of inverted repeat constructs for double-stranded RNA expression. [PDF]
PLoS ONE, 2009 BACKGROUND: RNA interference (RNAi) has emerged as a powerful tool for the targeted knockout of genes for functional genomics, system biology studies and drug discovery applications.
Brian Hauge +4 more
doaj +6 more sources