Results 91 to 100 of about 159,254 (282)

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Next-generation sequencing yields the complete chloroplast genome of Abies balsamea

Mitochondrial DNA. Part B. Resources, 2019
Abies balsamea is native to the mountains of North America and often used as Christmas Trees. In this study, we reported the complete chloroplast genome of A. balsamea.
Si Wu, Xiao-Fang Lu, Peng-Fei Zhao, Yi-Zhen Shao   +3 more
doaj   +1 more source

Abundant and species-specific DINE-1 transposable elements in 12 Drosophila genomes [PDF]

, 2008
Evidence is presented that DINE-1 is a highly abundant miniature inverted-repeat transposable element (MITE) family present in all 12 Drosophila species with whole-genome sequence ...
Barbash, Daniel A, Yang, Hsiao-Pei
core   +2 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Next-generation sequencing yields the complete chloroplast genome of Abies Alba

Mitochondrial DNA. Part B. Resources, 2019
Abies alba is native to the mountains of Europe and often used as Christmas trees. In this study, we reported the complete chloroplast genome of A. alba. The complete chloroplast genome is 121,243 bp in length, comprising a large single copy (LSC) region
Guo-Yin Li, Wen-Jiang Wu, Yun-Xia Zhang, Jian-Hang Mao, Ya-Jie Song, Xue-Yang Han, Ming-Hui Song, Zhen-Ni Guo, Ya-bin Dong, Xiao-Meng Liu   +9 more
doaj   +1 more source

Complete mitogenomes of the chlorophyte green algae Scherffelia dubia and Tetraselmis sp. CCMP 881 (Chlorodendrophyceae)

Mitochondrial DNA. Part B. Resources, 2020
We report here the first mitogenome sequences for the chlorophyte class Chlorodendrophyceae. The mitogenomes of Tetraselmis sp. CCMP 881 and Scherffelia dubia (SAG 17.86) are 46,904 bp and 78,958 bp long, respectively, but their gene repertoires are ...
Monique Turmel, Christian Otis, Jean-Charles de Cambiaire, Claude Lemieux   +3 more
doaj   +1 more source

Mechanism for inverted-repeat recombination induced by a replication fork barrier

Nature Communications, 2022
Replication stress and abundant repetitive sequences have emerged as primary conditions underlying genomic instability in eukaryotes. Here the authors use a prokaryotic Tus/Ter barrier designed to induce transient replication fork stalling near inverted ...
Léa Marie, Lorraine S. Symington
doaj   +1 more source

The Complete Nucleotide Sequence of the Coffee (Coffea Arabica L.) Chloroplast Genome: Organization and Implications for Biotechnology and Phylogenetic Relationships Amongst Angiosperms [PDF]

, 2007
The chloroplast genome sequence of Coffea arabica L., the first sequenced member of the fourth largest family of angiosperms, Rubiaceae, is reported. The genome is 155 189 bp in length, including a pair of inverted repeats of 25 943 bp.
Asano T., Ashihara H., Barton C., Bausher M.G., Carneiro M., Chang C.-C., Chumley T.W., Daniell H., Daniell H., Goremykin V.V., Goremykin V.V., Hupfer H., Jansen R.K., Jansen R.K., Kato T., Kim K.J., Lee S.-B., Lee S.M., Leelavathi S., Lockhart P.J., Maier R.M., Martin W., Mendez-Lopez I., Ocampo C., Ogihara Y., Palmer J.D., Penna S., Pereira L.F.P., Pombert J.-F., Raubeson L.A., Ribas A.F., Ruhlman T., Sandbrink J.M., Schmitz-Linneweber C., Shinozaki K., Soltis D.E., Soltis D.E., Spiral J., Steane D.A., Swofford D.L., USDA, Van Boxtel J., Van Boxtel J., Wakasugi T.   +43 more
core   +3 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Next-generation sequencing yields the complete chloroplast genome of Abies fanjingshanensis, an Endangered species from South China

Mitochondrial DNA. Part B. Resources, 2019
Abies fansipanensis is an Endangered species in South China with less than 2500 mature trees. In this study, we reported the complete chloroplast genome of A. fansipanensis.
Zhen-Ni Guo, Xiao-Fang Lu, Ya-bin Dong, Chang-Jing Wu, Guo-Yin Li   +4 more
doaj   +1 more source