Results 11 to 20 of about 77,899 (290)

Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification.

open access: yesPLoS Genetics, 2015
DNA replication errors are a major driver of evolution--from single nucleotide polymorphisms to large-scale copy number variations (CNVs). Here we test a specific replication-based model to explain the generation of interstitial, inverted triplications ...
Bonita J Brewer   +6 more
doaj   +4 more sources

Concentration of inverted repeats along human DNA

open access: yesJournal of Integrative Bioinformatics, 2023
This work aims to describe the observed enrichment of inverted repeats in the human genome; and to identify and describe, with detailed length profiles, the regions with significant and relevant enriched occurrence of inverted repeats.
Bastos Carlos A. C.   +3 more
doaj   +4 more sources

Stability of an inverted repeat in a human fibrosarcoma cell [PDF]

open access: greenNucleic Acids Research, 1996
Deletions and rearrangements of DNA sequences within the genome of human cells result in mutations associated with human disease. We have developed a selection system involving a neo gene containing a DNA sequence inserted into the NcoI site that can be used to quantitatively assay deletion of this sequence from the chromosome. The spontaneous deletion
Phillip R. Kramer
openalex   +5 more sources

The Loss of the Inverted Repeat in the Putranjivoid Clade of Malpighiales. [PDF]

open access: yesFront Plant Sci, 2020
The typical plastid genome (plastome) of photosynthetic angiosperms comprises a pair of Inverted Repeat regions (IRs), which separate a Large Single Copy region (LSC) from a Small Single Copy region (SSC). The independent losses of IRs have been documented in only a few distinct plant lineages.
Jin DM   +5 more
europepmc   +6 more sources

INVERTED REPEATS IN VIRAL GENOMES [PDF]

open access: yesFluctuation and Noise Letters, 2005
We investigate 738 complete genomes of viruses to detect the presence of short inverted repeats. The number of inverted repeats found is compared with the prediction obtained for a Bernoullian and for a Markovian control model. We find as a statistical regularity that the number of observed inverted repeats is often greater than the one expected in ...
Rosario N. Mantegna   +3 more
openaire   +4 more sources

Leaping forks at inverted repeats: Figure 1. [PDF]

open access: yesGenes & Development, 2010
Genome rearrangements are often associated with genome instability observed in cancer and other pathological disorders. Different types of repeat elements are common in genomes and are prone to instability. S-phase checkpoints, recombination, and telomere maintenance pathways have been implicated in suppressing chromosome rearrangements, but little is ...
D. Branzei, M. Foiani
openaire   +3 more sources

Inverted and mirror repeats in model nucleotide sequences [PDF]

open access: greenPhysical Review E, 2007
We analytically and numerically study the probabilistic properties of inverted and mirror repeats in model sequences of nucleic acids. We consider both perfect and non-perfect repeats, i.e. repeats with mismatches and gaps. The considered sequence models are independent identically distributed (i.i.d.) sequences, Markov processes and long range ...
Fabrizio Lillo, M. Spanò
openalex   +6 more sources

The Excess of Small Inverted Repeats in Prokaryotes [PDF]

open access: yesJournal of Molecular Evolution, 2008
Recent analyses have shown that there is a large excess of perfect inverted repeats in many prokaryotic genomes but not in eukaryotic ones. This difference could be due to a genuine difference between prokaryotes and eukaryotes or to differences in the methods and types of data analyzed--full genome versus protein coding sequences.
Emmanuel D. Ladoukakis   +2 more
openaire   +3 more sources

Identification of the transcriptional regulator NcrB in the nickel resistance determinant of Leptospirillum ferriphilum UBK03. [PDF]

open access: yesPLoS ONE, 2011
The nickel resistance determinant ncrABCY was identified in Leptospirillum ferriphilum UBK03. Within this operon, ncrA and ncrC encode two membrane proteins that form an efflux system, and ncrB encodes NcrB, which belongs to an uncharacterized family ...
Tao Zhu   +4 more
doaj   +1 more source

The first discovery of Tc1 transposons in yeast

open access: yesFrontiers in Microbiology, 2023
BackgroundIdentification of transposons without close homologs is still a difficult task. IS630/Tc1/mariner transposons, classified into a superfamily, are probably the most widespread DNA transposons in nature.
Jia Chang   +10 more
doaj   +1 more source

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