Results 301 to 310 of about 1,046,746 (344)
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Dimerization of v-erbA on inverted repeats
Biochemical and Biophysical Research Communications, 2002Thyroid hormone receptors (TRs) and the oncoprotein v-erbA can heterodimerize with retinoid X receptor (RXR) on core motifs arranged as inverted repeats (IR0) which contain the consensus sequence AGGTCA. On this core motif, v-erbA can also form homodimers whereas TRs homodimerize very poorly.
Inna, Zubkova, Jose S, Subauste
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Inverted repeat sequences in the drosophila genome
Cell, 1975The properties of inverted repeat (foldback) sequences in Drosophila melanogaster DNA have been studied by HAP chromatography and electron microscope methods. Electron microscope observations show that there is a broad distribution of lengths of the duplex regions of the inverted repeats from very short to greater than 15 kb, with number and weight ...
C W, Schmid, J E, Manning, N, Davidson
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DNA inverted repeats and human disease
Frontiers in Bioscience, 1998Inverted repeats are important elements in the human genome. Because of their nature, inverted repeats can engage in intra- and intermolecular basepairing. The ability to adopt hairpin and cruciform secondary structures is associated with frameshift mutations.
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Cloning and Sequencing an Inverted Repeat
Cold Spring Harbor Protocols, 2009INTRODUCTIONRNA interference (RNAi) is a suitable method for sequence-specific post-transcriptional gene silencing for a number of model systems. The production of a transgene for transgenic RNAi in mouse can be accomplished by cloning an inverted repeat (IR) into the Zp3 transgenic cassette.
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Mutational analysis of the inverted repeats of Tn3
Journal of Molecular Biology, 1990The transposase protein and the terminal inverted repeat sequences of the prokaryotic transposon Tn3 are essential for transposition. In order to determine the sequences within the inverted repeat necessary for transposition and interaction with transposase, we have constructed a series of mini-Tn3s in which specific mutations have been introduced into
D V, Nissley, F G, Lindh, M A, Fennewald
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Eukaryotic transposable elements with short terminal inverted repeats
Current Opinion in Genetics & Development, 1991Transposable elements with short terminal inverted repeats are believed to transpose directly from DNA to DNA via excision and integration. The cis/trans requirements for transposition have recently been characterized for some of these elements. Common features seem to emerge for the mechanisms of excision of these elements, with the mechanisms ...
A, Gierl, M, Frey
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Ebb and flow of the chloroplast inverted repeat
Molecular and General Genetics MGG, 1996The endpoints of the large inverted repeat (IR) of chloroplast DNA in flowering plants differ by small amounts between species. To quantify the extent of this movement and define a possible mechanism for IR expansion, DNA sequences across the IR-large single-copy (IR-LSC) junctions were compared among 13 Nicotiana species and other dicots.
S E, Goulding +3 more
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Eucaryotic transposable genetic elements with inverted terminal repeats
Cell, 1980DNA carrying inverted repeats was tested for transposition within the Drosophila genome. Five Bam HI segments containing related inverted repeats were isolated from D. melanogaster and analyzed by electron microscopy and restriction mapping. Southern blot experiments using single-copy flanking sequences as probes allowed the study of DNA arrangements ...
S, Potter +3 more
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Inverted repeats direct repair of adenovirus minichromosome ends
Virology, 1991Adenovirus DNA initiates strand-displacement replication from origins located in identical inverted terminal repetitions (ITRs). Panhandle structures, formed by base pairing between ITRs on the displaced strands, have been proposed as replication intermediates for complementary strand synthesis.
K, Wang +3 more
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More duplications via adjacent inverted repeat sequences
Journal of Molecular Biology, 1988Abstract Two previously characterized duplications in the insertion element IS2 of Escherichia coli can be described as end-products resulting from endonucleolytic cleavages of DNA at regions of potential secondary structure and subsequent DNA synthesis.
William H. McClain, Yong-Min Chen
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