Inverted repeat domains in membrane proteins
With the upsurge in known membrane protein structures, common structural themes have started to emerge. One of these is the inverted repeat, a tandem of α‐helical domains that have similar tertiary folds but opposite membrane orientations. In all previously known examples, both repeat units were encoded in a single continuous polypeptide.
Geoffrey Chang, Owen Pornillos
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DNA uptake sequences in 'Neisseria gonorrhoeae' as intrinsic transcriptional terminators and markers of horizontal gene transfer [PDF]
DNA uptake sequences are widespread throughout the Neisseria gonorrhoeae genome. These short, conserved sequences facilitate the exchange of endogenous DNA between members of the genus Neisseria.
Bentley+5 more
core +1 more source
Comparative genomics study of inverted repeats in bacteria [PDF]
Abstract Motivation: Comparative genomics provides a powerful way to investigate regularities and differences observed at DNA level across species. Here we study the number and location of inverted repeats occurring in complete genomes of bacteria.
Salvatore Basile+2 more
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Inverted repeat (IR) regions in the plastomes from land plants induce homologous recombination, generating isomeric plastomes. While the plastomes of Taxaceae species often lose one of the IR regions, considerable isomeric plastomes were created in ...
Yue Zhang+5 more
doaj +1 more source
A novel class of miniature inverted repeat transposable elements (MITEs) that contain hitchhiking (GTCY)n microsatellites [PDF]
The movement of miniature inverted repeat transposable elements (MITEs) modifies genome structure and function. We describe the microsatellite-associated interspersed nuclear element 2 (MINE-2), that integrates at consensus WTTTT target sites, creates ...
Anthony+69 more
core +3 more sources
Data‐driven performance metrics for neural network learning
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri+2 more
wiley +1 more source
Miniature inverted repeat transposable element (MITE) is a short transposable element, carrying no protein-coding regions. However, its high proliferation rate and sequence-specific insertion preference renders it as a good genetic tool for both natural ...
Ge Ruiquan+5 more
doaj +1 more source
Long-reads reveal that Rhododendron delavayi plastid genome contains extensive repeat sequences, and recombination exists among plastid genomes of photosynthetic Ericaceae [PDF]
Background Rhododendron delavayi Franch. var. delavayi is a wild ornamental plant species in Guizhou Province, China. The lack of its plastid genome information seriously hinders the further application and conservation of the valuable resource.
Huie Li, Qiqiang Guo, Qian Li, Lan Yang
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A role for non-B DNA forming sequences in mediating microlesions causing human inherited disease [PDF]
Missense/nonsense mutations and micro-deletions/micro-insertions of
Aguilera+86 more
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Long-read sequencing reveals atypical mitochondrial genome structure in a New Zealand marine isopod
Most animal mitochondrial genomes are small, circular and structurally conserved. However, recent work indicates that diverse taxa possess unusual mitochondrial genomes.
William S. Pearman+4 more
doaj +1 more source