Results 31 to 40 of about 1,046,746 (344)

Long-read sequencing reveals atypical mitochondrial genome structure in a New Zealand marine isopod

open access: yesRoyal Society Open Science, 2022
Most animal mitochondrial genomes are small, circular and structurally conserved. However, recent work indicates that diverse taxa possess unusual mitochondrial genomes.
William S. Pearman   +4 more
doaj   +1 more source

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats [PDF]

open access: yesNature, 2012
Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCRs) and copy-number variations (CNVs). GCRs and CNVs underlie human genomic disorders and are a feature of cancer. During cancer development, environmental factors and oncogene-driven proliferation promote replication stress.
Mizuno, Ken’Ichi   +4 more
openaire   +2 more sources

Bridging PCR: An Efficient and Reliable Scheme Implemented for Genome-Walking

open access: yesCurrent Issues in Molecular Biology, 2023
The efficacy of the available genome-walking methods is restricted by low specificity, high background, or composite operations. We herein conceived bridging PCR, an efficient genome-walking approach.
Zhiyu Lin   +3 more
doaj   +1 more source

Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster. [PDF]

open access: yesPLoS ONE, 2012
Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.
Raquel S Linheiro, Casey M Bergman
doaj   +1 more source

Blocking oligonucleotides improve sequencing through inverted repeats [PDF]

open access: yesBioTechniques, 2003
1.Fajkus, J., M. Simickova, and J. Malaska. 2002. Tiptoeing to chromosome tips: facts, promises and perils of today‘s human telomere biology. Philos. Trans. R. Soc. Lond. B Biol. Sci. 357:545-562. 2.Kim, N.W., M.A. Piatyszek, K.R. Prowse, C.B. Harley, M.D. West, P.L. Ho, G.M. Coviello, W.E. Wright, et al. 1994.
Dominic Esposito   +2 more
openaire   +3 more sources

Fast cloning inverted repeats for RNA interference [PDF]

open access: yesRNA, 2006
Double-stranded RNA (dsRNA) can induce post-transcriptional gene silencing in a wide variety of organisms. Commonly, inverted repeats are used to produce dsRNA to silence genes of interest. However, cloning inverted repeats still remains a rate-limiting step for widely applying this technique.
Bao, Sujin, Cagan, Ross L
openaire   +3 more sources

Insertion of miniature subterminal inverted repeat-like elements in diapause-regulated genes in the Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae)

open access: yesEuropean Journal of Entomology, 2011
Determining the genomic structure of diapause-associated transcripts (DAT) -2 and -3 led to the isolation of four novel miniature subterminal inverted repeat-like elements (MSITE): Mild-1, -2, -3 and -4.
George D. YOCUM   +3 more
doaj   +1 more source

Full-length chloroplast genome of Dongxiang wild rice reveals small single-copy region switching

open access: yesFrontiers in Plant Science, 2022
BackgroundPlant chloroplast DNA (cpDNA) typically has a circular structure, including a large single-copy region (LSC), a small single-copy region (SSC) and two inverted repeats (IR1 and IR2). The organization of these four elementary regions LSC-IR1-SSC-
Jianguang Liang   +8 more
doaj   +1 more source

The Unusual Properties of the AAV Inverted Terminal Repeat

open access: yesHuman Gene Therapy, 2020
Although the sequence of the AAV inverted terminal repeat has been known for 40 years, there are still unanswered questions about functions attributable to the terminal 125 nucleotides.
K. Berns
semanticscholar   +1 more source

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