Results 51 to 60 of about 159,254 (282)

IUPACpal: efficient identification of inverted repeats in IUPAC-encoded DNA sequences

open access: yesBMC Bioinformatics, 2021
Background An inverted repeat is a DNA sequence followed downstream by its reverse complement, potentially with a gap in the centre. Inverted repeats are found in both prokaryotic and eukaryotic genomes and they have been linked with countless possible ...
Hayam Alamro   +4 more
doaj   +1 more source

Conformational and thermodynamic hallmarks of DNA operator site specificity in the copper sensitive operon repressor from Streptomyces lividans [PDF]

open access: yes, 2014
Metal ion homeostasis in bacteria relies on metalloregulatory proteins to upregulate metal resistance genes and enable the organism to preclude metal toxicity.
Tan, BG, Vijgenboom, E, Worrall, JAR
core   +2 more sources

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats [PDF]

open access: yesNature, 2012
Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCRs) and copy-number variations (CNVs). GCRs and CNVs underlie human genomic disorders and are a feature of cancer. During cancer development, environmental factors and oncogene-driven proliferation promote replication stress.
Ken-ichi Mizuno   +4 more
openaire   +3 more sources

Detection of self-complementary inverted repeats by single forward primer driven PCR [PDF]

open access: yes, 2014
Inverted repeat gene structures designed for silencing functional genes have been widely used both in academic and applied research. The correct orientations of such structures are usually validated with restriction analysis and/or sequencing.
Bisztray, György Dénes   +3 more
core   +3 more sources

Directed Repeats Co-occur with Few Short-Dispersed Repeats in Plastid Genome of a Spikemoss, Selaginella vardei (Selaginellaceae, Lycopodiopsida)

open access: yesBMC Genomics, 2019
Background It is hypothesized that the highly conserved inverted repeats (IR) structure of land plant plastid genomes (plastomes) is beneficial for stabilizing plastome organization, whereas the mechanism of the occurrence and stability maintenance of ...
Hong-Rui Zhang   +2 more
doaj   +1 more source

The complete chloroplast genome of Aegle marmelos and its phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2023
Aegle marmelos (L.) Correa 1800, a plant belonging to the Rutaceae family, is extensively used in Tibetan medicine. We employed Illumina HiSeq reads to assemble the complete chloroplast (cp) genome of A. marmelos, which spans 144,538 bp.
Sijia Wang   +6 more
doaj   +1 more source

Functional Organization of the Inverted Repeats of IS30 [PDF]

open access: yesJournal of Bacteriology, 2010
ABSTRACTThe mobile element IS30has 26-bp imperfect terminal inverted repeats (IRs) that are indispensable for transposition. We have analyzed the effects of IR mutations on both major transposition steps, the circle formation and integration of the abutted ends, characteristic for IS30.
Szabó, Mónika   +2 more
openaire   +3 more sources

Variability of Inverted Repeats in All Available Genomes of Bacteria

open access: yesMicrobiology Spectrum, 2023
Our manuscript reports for the first time a complete analysis of inverted repeats in all fully sequenced bacterial genomes. Thanks to the availability of unique computational resources, we were able to statistically evaluate the presence and localization of these important regulatory sequences in bacterial genomes. This work revealed a strong abundance
Otília Porubiaková   +9 more
openaire   +6 more sources

Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism [PDF]

open access: yes, 1983
Poly(dG-dC)· poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are
Barton, Jacqueline K.   +5 more
core   +1 more source

Fast cloning inverted repeats for RNA interference [PDF]

open access: yesRNA, 2006
Double-stranded RNA (dsRNA) can induce post-transcriptional gene silencing in a wide variety of organisms. Commonly, inverted repeats are used to produce dsRNA to silence genes of interest. However, cloning inverted repeats still remains a rate-limiting step for widely applying this technique.
Bao, Sujin, Cagan, Ross L
openaire   +4 more sources

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