IUPACpal: efficient identification of inverted repeats in IUPAC-encoded DNA sequences
Background An inverted repeat is a DNA sequence followed downstream by its reverse complement, potentially with a gap in the centre. Inverted repeats are found in both prokaryotic and eukaryotic genomes and they have been linked with countless possible ...
Hayam Alamro+4 more
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Conformational and thermodynamic hallmarks of DNA operator site specificity in the copper sensitive operon repressor from Streptomyces lividans [PDF]
Metal ion homeostasis in bacteria relies on metalloregulatory proteins to upregulate metal resistance genes and enable the organism to preclude metal toxicity.
Tan, BG, Vijgenboom, E, Worrall, JAR
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Recombination-restarted replication makes inverted chromosome fusions at inverted repeats [PDF]
Impediments to DNA replication are known to induce gross chromosomal rearrangements (GCRs) and copy-number variations (CNVs). GCRs and CNVs underlie human genomic disorders and are a feature of cancer. During cancer development, environmental factors and oncogene-driven proliferation promote replication stress.
Ken-ichi Mizuno+4 more
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Detection of self-complementary inverted repeats by single forward primer driven PCR [PDF]
Inverted repeat gene structures designed for silencing functional genes have been widely used both in academic and applied research. The correct orientations of such structures are usually validated with restriction analysis and/or sequencing.
Bisztray, György Dénes+3 more
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Background It is hypothesized that the highly conserved inverted repeats (IR) structure of land plant plastid genomes (plastomes) is beneficial for stabilizing plastome organization, whereas the mechanism of the occurrence and stability maintenance of ...
Hong-Rui Zhang+2 more
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The complete chloroplast genome of Aegle marmelos and its phylogenetic analysis
Aegle marmelos (L.) Correa 1800, a plant belonging to the Rutaceae family, is extensively used in Tibetan medicine. We employed Illumina HiSeq reads to assemble the complete chloroplast (cp) genome of A. marmelos, which spans 144,538 bp.
Sijia Wang+6 more
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Functional Organization of the Inverted Repeats of IS30 [PDF]
ABSTRACTThe mobile element IS30has 26-bp imperfect terminal inverted repeats (IRs) that are indispensable for transposition. We have analyzed the effects of IR mutations on both major transposition steps, the circle formation and integration of the abutted ends, characteristic for IS30.
Szabó, Mónika+2 more
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Variability of Inverted Repeats in All Available Genomes of Bacteria
Our manuscript reports for the first time a complete analysis of inverted repeats in all fully sequenced bacterial genomes. Thanks to the availability of unique computational resources, we were able to statistically evaluate the presence and localization of these important regulatory sequences in bacterial genomes. This work revealed a strong abundance
Otília Porubiaková+9 more
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Lack of Z-DNA Conformation in Mitomycin-Modified Polynucleotides Having Inverted Circular Dichroism [PDF]
Poly(dG-dC)· poly(dG-dC) and Micrococcus lysodeikticus DNA were modified by exposure to reductively activated mitomycin C, an antitumor antibiotic. The resulting covalent drug-polynucleotide complexes displayed varying degrees of CD inversions, which are
Barton, Jacqueline K.+5 more
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Fast cloning inverted repeats for RNA interference [PDF]
Double-stranded RNA (dsRNA) can induce post-transcriptional gene silencing in a wide variety of organisms. Commonly, inverted repeats are used to produce dsRNA to silence genes of interest. However, cloning inverted repeats still remains a rate-limiting step for widely applying this technique.
Bao, Sujin, Cagan, Ross L
openaire +4 more sources