Results 81 to 90 of about 159,254 (282)

The Prevalence and Evolutionary Conservation of Inverted Repeats in Proteobacteria

Genome Biology and Evolution, 2018
Perfect short inverted repeats (IRs) are known to be enriched in a variety of bacterial and eukaryotic genomes. Currently, it is unclear whether perfect IRs are conserved over evolutionary time scales. In this study, we aimed to characterize the prevalence and evolutionary conservation of IRs across 20 proteobacterial strains.
Eli Levy Karin, Einat Hazkani-Covo, Tal Pupko, Bar Lavi, Bar Lavi   +4 more
openaire   +3 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Intramolecular integration within Moloney murine leukemia virus DNA [PDF]

, 1981
By screening a library of unintegrated, circular Moloney murine leukemia virus (M-MuLV) DNA cloned in lambda phage, we found that approximately 20% of the M-MuLV DNA inserts contained internal sequence deletions or inversions.
Baltimore, David, Goff, Stephen P., Hoffmann, Joseph, Shoemaker, Charles   +3 more
core  

Transfer origins in the conjugative Enterococcus faecalis plasmids pAD1 and pAM373: identification of the pAD1 nic site, a specific relaxase and a possible TraG-like protein [PDF]

, 2002
The Enterococcus faecalis conjugative plasmids pAD1 and pAM373 encode a mating response to the peptide sex pheromones cAD1 and cAM373 respectively. Sequence determination of both plasmids has recently been completed with strong similarity evident over ...
Arthur M., Balzer D., Berg T., Bhattacharjee M., Broome-Smith J., Chow J.W., Clewell D.B., Clewell D.B., Clewell D.B., Clewell D.B., Clewell D.B., Clewell D.B.,, Clewell D.B.,, Clewell D.B.,, Climo M.W., de la Cruz F.,, del Solar G., Dower W.J., Dunny G.M., Erickson M.J.,, Evers S., Firth N., Firth N., Flannagan S.E.,, Flannagan S.E.,, Franke A.E.,, Galli D., Gilmore M.S., Hanahan D., Heath D.G., Ike Y.,, Inselburg J., Jacob A.E.,, Jensen L.B., Jones J.M., Kreft B., Laemmli U.K., Llosa M., Pansegrau W., Pansegrau W., Pansegrau W., Pontius L.T.,, Possoz C., Sambrook J., Schaberg D.R., Smith C.J.,, Tenover F.C., Tenover F.C., van Kranenburg R.,, Walker J.E., Wang A.,, Warren G.J., Waters V.L.,, Weaver K.E., Weaver K.E.,, Wilkins B.M.,, Willems R.J., Willetts N.,, Wirth R., Yagi Y.,, Zechner E.L., Zhang S.,   +61 more
core   +1 more source

Complete chloroplast genome sequencing of Caralluma quadrangula and comparative analysis of the Asclepiadoideae subfamily (Apocynaceae) [PDF]

, 2021
Caralluma quadrangula is an herbaceous plant distributed in Saudi Arabia, India, Africa, and the Canary Islands. To assess the phylogenetic and evolutionary relationships among the Asclepiadoideae subfamily in the Apocynaceae family, we carried out a ...
Abba, Abidina, Albokhari, Enas J., Alzahrani, Dhafer A., Yaradua, Samaila S.   +3 more
core   +2 more sources

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase δ-dependent mechanism

Nature Communications, 2023
Inverted duplications, also known as foldback inversions, are commonly observed in cancers and are the major class of chromosome rearrangement recovered from yeast cells lacking Mre11 nuclease activity. Foldback priming at DNA double-strand breaks (DSBs)
Amr M. Al-Zain, Mattie R. Nester, Iffat Ahmed, Lorraine S. Symington   +3 more
doaj   +1 more source

Secondary structures in polyoma DNA [PDF]

, 1979
Three reproducible secondary-structure features were observed on single strands of polyoma virus DNA mounted for electron microscopy by the T4 gene 32 protein technique: (i) a hairpin fold-back extending from 92.9 +/- 0.8 to 95.0 +/- 0.7 map units; (ii ...
Davidson, Norman, Manor, Haim, Wu, Madeline   +2 more
core  

Epstein Barr Virus genome variation and functional analysis of the IR-1 internal repeat [PDF]

, 2018
Epstein Barr Virus (EBV), a human gammaherpesvirus, establishes lifelong infection in B lymphocytes and is associated with a variety of malignancies including; Hodgkin's lymphoma, Burkitt's lymphoma and nasopharyngeal carcinoma. Due to the differences in
Correia, Samantha
core   +1 more source

Unique Tandem Repeats in the Inverted Terminal Repeat Regions of Monkeypox Viruses

Microbiology Spectrum, 2023
The different groups of MPXVs contain unique tandem repeats with different copy numbers in the ITR regions, and these repeats may be likely to play a role in the genetic diversity of the virus. Clade IIb (B) MPXV contains 38 and 32 repeats similar to the Tandem repeats reported in the human and rodent genome, respectively.
Perumal Arumugam Desingu, K. Nagarajan, Nagalingam R. Sundaresan   +2 more
openaire   +2 more sources