Results 81 to 90 of about 212,695 (330)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Novel ZVS S-TCM Modulation of Three-Phase AC/DC Converters
IEEE Open Journal of Power Electronics, 2020 For three-phase AC-DC power conversion, the widely-used continuous current mode (CCM) modulation scheme results in relatively high semiconductor losses from hard-switching each device during half of the mains cycle.
Michael Haider +7 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
EnergiesThis paper extends one of the nonswitching-type reaching laws for discrete-time sliding mode control. The control task under consideration is the regulation of the grid current of the grid-following power inverter.
Albert Sawiński +2 more
doaj +1 more source
Microfluidic electro‐viscoelastic manipulation of extracellular vesicles
FEBS Open Bio, EarlyView.The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh +7 more
wiley +1 more source
Implementing Wireless Charging System for Semi-Autonomous Agricultural Robots
EnergiesThe modernization of agriculture can help humanity address major challenges such as population growth, climate change, and labor shortages. Semi-autonomous agricultural robots offer clear advantages in automating tasks and improving efficiency.
Abdoulaye Bodian +4 more
doaj +1 more source
Development and validation of apparent diffusion coefficient histogram-based nomogram for predicting malignant transformation of sinonasal inverted papilloma [PDF]
, 2023 Meng Qi +4 more
openalex +1 more source
FEBS Open Bio, EarlyView.Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah +8 more
wiley +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Applied SciencesThe integration of inverter-based resources (IBRs) is reshaping power grid operation by reducing system inertia, which impacts small-signal rotor angle stability and increases low-frequency oscillations (LFOs).
Markel Zubiaga +4 more
doaj +1 more source