Results 71 to 80 of about 27,323 (272)

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

Salinity Indian Ocean Dipole: Another facet of the Indian Ocean Dipole phenomenon from satellite remote sensing

open access: yesScience of Remote Sensing
Using satellite-measured sea surface salinity (SSS) from the Aquarius and Soil Moisture Active Passive (SMAP) missions since 2011, we show that SSS in the Equatorial Indian Ocean (EIO) experienced dipolar changes in the well-defined east EIO and west EIO
Wei Shi, Menghua Wang
doaj   +1 more source

Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam   +15 more
wiley   +1 more source

Establishment and Comparative Analysis of Radiation‐Induced Liver Disease in Normal and Fibrotic Rat Models

open access: yesPrecision Radiation Oncology, EarlyView.
This study successfully established two novel rat models of radiation‐induced liver disease (RILD), one in healthy livers and the other in TAA‐induced fibrotic livers, providing valuable insights into the combined effects of radiation and pre‐existing fibrosis.
Yanting Jiang   +9 more
wiley   +1 more source

Meteorological conditions leading to a catastrophic, rain‐induced landslide in Cameroon in October 2019

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
October 2019 was characterized by three main multiday wet spells in Bafoussam and Dschang. Our results indicated that wet spells were influenced by a vortex pair near the Gulf of Guinea, a strong Sahara Heat Low located anomalously far east and north, a northward shift of the intertropical discontinuity, an enhancement of the inland penetration of the ...
Derbetini A. Vondou   +3 more
wiley   +1 more source

Future changes in rainfall associated with ENSO, IOD and changes in the mean state over Eastern Africa

open access: yesClimate Dynamics, 2019
This study examines the projected changes in the characteristics of the El Niño Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD) in terms of mean state, intensity and frequency, and associated rainfall anomalies over eastern Africa. Two regional
H. S. Endris   +5 more
semanticscholar   +1 more source

The role of soil moisture in the inland penetration of Indian monsoon low‐pressure systems

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We use the Advanced Weather Research and Forecasting model to examine the role of soil moisture in the inland penetration of Indian monsoon low‐pressure systems (LPSs). We find that LPSs penetrate deeply into India despite a dry land surface; however, their inland penetration is adversely affected when there is a reduction in the total surface heat ...
Akshay Deoras   +2 more
wiley   +1 more source

Impact of ENSO and IOD Climate Variability on the Dynamics of Bullet Tuna (Auxis rochei) Catches in the Banda Sea [PDF]

open access: yesBIO Web of Conferences
The Banda Sea is a tropical marine region in Indonesia with complex oceanographic dynamics and high productivity, serving as a key habitat for pelagic fish such as bullet tuna (Auxis rochei).
Srioktoviana Siti Khadijah   +5 more
doaj   +1 more source

Causal effects of Indian Ocean Dipole on El Niño–Southern Oscillation during 1950–2014 based on high-resolution models and reanalysis data

open access: yesEnvironmental Research Letters, 2020
Uncertainty exists regarding the interaction between the El Niño–Southern Oscillation (ENSO) and Indian Ocean Dipole (IOD) where ENSO is normally expected to be the leading mode.
Thanh Le   +3 more
doaj   +1 more source

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