Results 81 to 90 of about 165,016 (280)

Designing Strong, Tough, Fire‐Retardant and Self‐Healing Elastomers with Phosphorus/Nitrogen‐ and Biphenyl‐Containing Segments

Advanced Materials, EarlyView.
By designing a P/N‐ and π–π interacting biphenyl‐containing diol as hard segments but side groups, a strong, tough, fire‐extinguishing and self‐healing elastomer is developed, demonstrating a break strain of ∼2500%, a toughness of 379 MJ/m3 and a tensile strength of 46 MPa, as well as a healing efficiency of 95% (tensile strength) and 99% (break strain)
Yijiao Xue, Shu Gong, Zhezhe Zhou, Zhewen Ma, Yanlong Luo, Mark Lynch, Jiabing Feng, Yan Zhang, Meng Zhang, Yonghong Zhou, Wenlong Cheng, Pingan Song   +11 more
wiley   +1 more source

β-Lactoglobulin separation from whey protein: A comprehensive review of isolation and purification techniques and future perspectives

Journal of Dairy Science
: Cow milk, although rich in essential nutrients, is a well-known food allergen that can cause allergic reactions in infants and young children. β-Lactoglobulin accounts for 10% of the total protein in milk and 50% of the whey protein, which has high ...
Z.L. Wang, X. Tang, M. Wang, Y.X. She, B.R. Yang, Q.H. Sheng, A.M. Abd El-Aty   +6 more
doaj   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

The derivation of bioprocess understanding from mechanistic models of chromatography

, 2015
This thesis, completed in collaboration with Purification Process Development of Pfizer Biotherapeutics, is concerned with how mechanistic models of chromatographic bioseparations can be applied in industry to accelerate development and increase ...
Close, EJ
core  

Improvement in protein separation by pH excursion modulated ion-exchange chromatography

Journal of Chromatography Open
The transient change in pH during the elution step in ion exchange chromatography is commonly referred to as pH excursion. Acidic pH excursion is usually observed during salt-based elution in cation exchange chromatography.
Raja Ghosh
doaj   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Rapid ion-exchange chromatography for preparative separation of proteins IV. Application to bovine carbonic anhydrase III from skeletal muscle

, 1991
Bovine muscle carbonic anhydrase III was purified to homogeneity by the strategy of rapid ion-exchange chromatography. The ionic exchanger used was CM-cellulose, and this is the first application of this technique on a cation exchanger.
Kristina Borén, Borén, Kristina,, Uno Carlsson, Nils Bergenhem, Bergenhem, Nils,, Carlsson, Uno,, Marie Larsson, Larsson, Marie,   +7 more
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Design of two-column batch-to-batch recirculation to enhance performance in ion-exchange chromatography

, 2018
Preparative liquid chromatography is a separation technique widely used in the manufacturing of fine chemicals and pharmaceuticals. A major drawback of traditional single-column batch chromatography step is the trade-off between product purity and ...
Nilsson, Bernt,, Lund University., Andersson, Niklas,, Persson, Oliver,   +3 more
core   +1 more source