Results 181 to 190 of about 145,291 (286)

Selective Scandium Elution from D₂EHPA-Impregnated Ion-Exchange Resin After Metal Loading from Acidic Chloride Solutions. [PDF]

Materials (Basel)
Mikeli E, Marinos D, Balomenos E, Panias D.   +3 more
europepmc   +1 more source

Adaptive Machine Learning Framework for Optimizing the Affinity Purification of Adeno‐Associated Viral Vectors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adeno‐associated viral (AAV) vectors for gene therapy are becoming integral to modern medicine, providing therapeutic options for diseases once deemed incurable. Currently, viral vector purification is a critical bottleneck in the gene therapy industry, impacting product efficacy and safety as well as accessibility and cost to patients ...
Kelvin P. Idanwekhai, Shriarjun Shastry, Morgan R. Hurst, Arianna Minzoni, Eduardo Barbieri, Luke Remmler, Eugene N. Muratov, Michael A. Daniele, Stefano Menegatti, Alexander Tropsha   +9 more
wiley   +1 more source

Reaction Thermodynamic and Kinetics for Esterification of 1-Methoxy-2-Propanol and Acetic Acid over Ion-Exchange Resin. [PDF]

Molecules
Liu X, Wang S, Wang M, Chen L, Qi Z.
europepmc   +1 more source

Development of Raman Spectroscopy and Machine Learning Methods for Protein Aggregate Quantification: Application to BSA in Chromatographic Processes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Protein aggregation poses a significant risk to biopharmaceutical product quality, as even minor amounts of oligomeric species can compromise efficacy and safety. Rapid and reliable detection of protein aggregates thus remains a major challenge in biopharmaceutical manufacturing.
Jakob Heyer‐Müller, Robin Schiemer, Lars Robbel, Michael Schmitt, Jürgen Hubbuch   +4 more
wiley   +1 more source

Correction to "Ion-Exchange Resin/Carrageenan-Copper-Based Nanocomposite: Artificial Neural Network, Advanced Thermodynamic Profiling, and Anticoagulant Studies". [PDF]

ACS Omega
Haider S, Ullah S, Kazi M, Qamar F, Siddique T, Anwer R, Khan SA, Salman S.   +7 more
europepmc   +1 more source

The effect of ion-exchange resin treatment on grape must composition and fermentation kinetics. [PDF]

Heliyon, 2020
Cisilotto B, Rossato SB, Ficagna E, Wetzstein LC, Gava A, Gugel GM, Echeverrigaray S.   +6 more
europepmc   +1 more source

Multimodal Chromatography in the Downstream Processing of mAb‐Based Products: Mechanisms, Strategies, and Applications

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan, Marco P․ C․ Marques, Ana M. Azevedo, Daniel G. Bracewell, Stephen Goldrick   +4 more
wiley   +1 more source

Adsorption Mechanisms of CO₂ on Macroporous Ion-Exchange Resin Organic Amine Composite Materials by the Density Functional Theory. [PDF]

ACS Omega
Li Y, Liu X, Guo Q.
europepmc   +1 more source

Separation and Purification of Biogenic 1,3-Propanediol from Fermented Glycerol through Flocculation and Strong Acidic Ion-Exchange Resin. [PDF]

Biomolecules, 2020
Mitrea L, Leopold LF, Bouari C, Vodnar DC.   +3 more
europepmc   +1 more source

Detergent Virus Inactivation in Chromatography Systems

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Detergent treatment is a widely utilized virus‐inactivation step in therapeutic protein manufacturing to safeguard products. Traditionally, this operation is performed in an incubation vessel in batch mode. In this investigation, a methodology was developed to enable virus inactivation via a post‐load, detergent‐containing wash within a bind ...
Kang Cai, Etienne Utiger, Chris Afdahl, Rayan Zamat, Jennifer Anderson, Yeldys De Armas, Gisela Ferreira   +6 more
wiley   +1 more source