Results 251 to 260 of about 2,447,449 (300)

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

A histidine-mediated supramolecular mechanism links temperature and pH activation of the sperm channel CatSper. [PDF]

PLoS Biol
Zhao B, Bhagwat S, Ferreira J, Ruff KM, Swain DK, Pappu RV, Santi CM, Fu Z, Lishko PV.   +8 more
europepmc   +1 more source

ASIC1a as an integrating node in ischemic neurotoxicity: crosstalk with NMDAR and TRPM signaling. [PDF]

Pflugers Arch
Lai K, Wang LY.
europepmc   +1 more source

Battery-Inspired Electrochemical Synapses for Neuromorphic Applications. [PDF]

Adv Sci (Weinh)
Lee WW, Jang S, Choi W, Park J, Hur J, Yoo H, Kim HS.   +6 more
europepmc   +1 more source

Piezo channels in physical field therapy: From mechanotransduction mechanisms to bioelectromagnetic modulation and biomedical applications. [PDF]

Mechanobiol Med
Li B, Kang HM, Pan WD, Li Y.
europepmc   +1 more source

Investigation and computational prediction of gating pore currents in Na_V1.2 mutations across clinical phenotypes. [PDF]

PNAS Nexus
Eltokhi A, Elhanafy E, Li J, Gamal El-Din TM.   +3 more
europepmc   +1 more source

Ion channel gating: insights via molecular simulations

FEBS Letters, 2003
Ion channels are gated, i.e. they can switch conformation between a closed and an open state. Molecular dynamics simulations may be used to study the conformational dynamics of ion channels and of simple channel models.
Philip C. Biggin, Mark S.P. Sansom, Carmen Domene   +2 more
exaly   +2 more sources