Results 81 to 90 of about 100,331 (293)

A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs). [PDF]

open access: yes, 1998
MinK and MinK-related peptide I (MiRPI) are integral membrane peptides with a single transmembrane span. These peptides are active only when co-assembled with pore-forming K+ channel subunits and yet their role in normal ion channel behaviour is ...
Abbott, GW, Goldstein, SA
core  

Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]

open access: yes, 2004
The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C   +17 more
core   +2 more sources

MOFs and COFs in Electronics: Bridging the Gap between Intrinsic Properties and Measured Performance

open access: yesAdvanced Functional Materials, EarlyView.
Metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs) hold promise for advanced electronics. However, discrepancies in reported electrical conductivities highlight the importance of measurement methodologies. This review explores intrinsic charge transport mechanisms and extrinsic factors influencing performance, and critically ...
Jonas F. Pöhls, R. Thomas Weitz
wiley   +1 more source

Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating.

open access: yesPLoS Biology, 2009
Ryanodine receptor type 1 (RyR1) produces spatially and temporally defined Ca2+ signals in several cell types. How signals received in the cytoplasmic domain are transmitted to the ion gate and how the channel gates are unknown.
Montserrat Samsó   +3 more
doaj   +1 more source

Mathematical Model Investigating the Effects of Neurostimulation Therapies on Neural Functioning: Comparing the Effects of Neuromodulation Techniques on Ion Channel Gating and Ionic Flux Using Finite Element Analysis [PDF]

open access: yes, 2019
Neurostimulation therapies demonstrate success as a medical intervention for individuals with neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease.
Lindberg, Kaia
core   +1 more source

Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus

open access: yes, 2007
The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus.
A. F. Huxley   +28 more
core   +2 more sources

Multicolor Optoelectronic Synapse Enabled by Photon‐Modulated Remote Doping in Solution‐Processed Van Der Waals Heterostructures

open access: yesAdvanced Functional Materials, EarlyView.
Multicolor optoelectronic synapses are realized by vertically integrating solution‐processed MoS2 thin‐film and SWCNT. The electronically disconnected but interactive MoS2 enables photon‐modulated remote doping, producing a bi‐directional photoresponse.
Jihyun Kim   +8 more
wiley   +1 more source

Ice Lithography: Recent Progress Opens a New Frontier of Opportunities

open access: yesAdvanced Functional Materials, EarlyView.
This review focuses on recent advancements in ice lithography, including breakthroughs in compatible precursors and substrates, processes and applications, hardware, and digital methods. Moreover, it offers a roadmap to uncover innovation opportunities for ice lithography in fields such as biological, nanoengineering and microsystems, biophysics and ...
Bingdong Chang   +9 more
wiley   +1 more source

The Outer Vestibule of the Na+ Channel–Toxin Receptor and Modulator of Permeation as Well as Gating

open access: yesMarine Drugs, 2010
The outer vestibule of voltage-gated Na+ channels is formed by extracellular loops connecting the S5 and S6 segments of all four domains (“P-loops”), which fold back into the membrane. Classically, this structure has been implicated in the control of ion
René Cervenka   +3 more
doaj   +1 more source

Stochastic Dynamics of Electrical Membrane with Voltage-Dependent Ion Channel Fluctuations

open access: yes, 2014
Brownian ratchet like stochastic theory for the electrochemical membrane system of Hodgkin-Huxley (HH) is developed. The system is characterized by a continuous variable $Q_m(t)$, representing mobile membrane charge density, and a discrete variable $K_t$
Qian, Hong, Qian, Min, Zhang, Xue-Juan
core   +1 more source

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