Results 81 to 90 of about 57,056 (243)

Motifs in the permeation pathway of connexin channels mediate Ca2+ and voltage sensing.

Frontiers in Physiology, 2014
Connexin channels mediate electrical coupling, intercellular molecular signaling and extracellular release of signaling molecules. Connexin proteins assemble intracellularly as hexamers to form plasma membrane hemichannels.
Andrew L. Harris, Jorge E. Contreras
doaj   +1 more source

Thermal Impact on Spiking Properties in Hodgkin-Huxley Neuron with Synaptic Stimulus

, 2007
The effect of environmental temperature on neuronal spiking behaviors is investigated by numerically simulating the temperature dependence of spiking threshold of the Hodgkin-Huxley neuron subject to synaptic stimulus.
A. F. Huxley, A. L. Hodgkin, A. L. Hodgkin, A. L. Hodgkin, A. V. Holden, Aiyin Cao, F. Bezanilla, H. Xu, J. D. Miller, J. J. C. Rosenthal, J. S. Rothman, J. S. Schweitzer, J. W. Moore, Jiafu Wang, M. I. Rabinovich, M. Radmilovich, M. Volgushev, R. A. Sjodin, R. FitzHugh, R. FitzHugh, R. Guttman, R. Guttman, R. VanRullen, S. Kuang, Shenbing Kuang, Ting Zeng, V. Y. Vasilenko, X. Cao, Y. Zhao   +28 more
core   +2 more sources

SI‐bioATRP in Mesoporous Silica for Size‐Exclusion Driven Local Polymer Placement

Advanced Functional Materials, EarlyView.
An enzyme‐catalyzed surface‐initiated atom transfer radical polymerization (SI‐bioATRP) of an anionic monomer within mesoporous silica particles, using hemoglobin as a catalyst, allows for controlling the location of the formed polymer via size‐exclusion effects between the nanopores and the biomacromolecules, thereby opening routes to functional ...
Oleksandr Wondra, Eleonora Ornati, Robert Lehn, Joanna J. Mikolei, Hergen Breitzke, Raheleh Pardehkhorram, Gerd Buntkowsky, Nico Bruns, Annette Andrieu‐Brunsen   +8 more
wiley   +1 more source

Stochastically gating ion channels enable patterned spike firing through activity-dependent modulation of spike probability.

PLoS Computational Biology, 2009
The transformation of synaptic input into patterns of spike output is a fundamental operation that is determined by the particular complement of ion channels that a neuron expresses.
Joshua T Dudman, Matthew F Nolan
doaj   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source

Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating.

PLoS Biology, 2009
Ryanodine receptor type 1 (RyR1) produces spatially and temporally defined Ca2+ signals in several cell types. How signals received in the cytoplasmic domain are transmitted to the ion gate and how the channel gates are unknown.
Montserrat Samsó, Wei Feng, Isaac N Pessah, P D Allen   +3 more
doaj   +1 more source

Stochastic Dynamics of Electrical Membrane with Voltage-Dependent Ion Channel Fluctuations

, 2014
Brownian ratchet like stochastic theory for the electrochemical membrane system of Hodgkin-Huxley (HH) is developed. The system is characterized by a continuous variable $Q_m(t)$, representing mobile membrane charge density, and a discrete variable $K_t$
Qian, Hong, Qian, Min, Zhang, Xue-Juan
core   +1 more source

Enhancing Synaptic Plasticity and Multistate Retention of Organic Neuromorphic Devices Using Anion‐Excessive Gel Electrolyte

Advanced Functional Materials, EarlyView.
Anion‐excessive gel‐based organic synaptic transistors (AEG‐OSTs) that can maintain electrical neutrality are developed to enhance synaptic plasticity and multistate retention. Key improvement is attributed to the maintenance of electrical neutrality in the electrolyte even after electrochemical doping, which reduces the Coulombic force acting on ...
Yousang Won, Jeongwoo Lee, Hyunwook Kim, Joon Hak Oh   +3 more
wiley   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

Advanced Science
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair bundles into electrical signals. The mechanical correlates of channel gating—the gating force and the gating swing—are fundamental determinants of hair ...
Achille Joliot, Laure Stickel, Pascal Martin   +2 more
doaj   +1 more source

Stochastic modeling of excitable dynamics: improved Langevin model for mesoscopic channel noise

, 2014
Influence of mesoscopic channel noise on excitable dynamics of living cells became a hot subject within the last decade, and the traditional biophysical models of neuronal dynamics such as Hodgkin-Huxley model have been generalized to incorporate such ...
Goychuk, Igor
core   +1 more source