Results 61 to 70 of about 3,686,327 (402)

Moringa oleifera (drumstick tree)—nutraceutical, cosmetological and medicinal importance: a review

Frontiers in Pharmacology
Moringa oleifera Lam. (Moringaceae) is a species of tree with an increasing utility, occurring naturally mainly in Pakistan and northern India. M. oleifera is currently cultivated in Africa, South America, Asia and the Middle East.
Marta Klimek-Szczykutowicz, Katarzyna Gaweł-Bęben, Angelika Rutka, Eliza Blicharska, Małgorzata Tatarczak-Michalewska, Katarzyna Kulik-Siarek, Wirginia Kukula-Koch, Magdalena Anna Malinowska, Agnieszka Szopa   +8 more
doaj   +1 more source

Development and application of an UHPLC-MS/MS method for the simultaneous determination of 17 steroidal hormones in equine serum [PDF]

, 2017
A new, fast and simple analytical method that is able to identify and quantify simultaneously 17 steroid hormones and metabolites (Pregnenolone, 17-OH-Pregnenolone, Progesterone, 17-OH Progesterone, Androsterone, Androstenedione, DHEA, DHEAS ...
Allis, Bonfiglio, Büttler, Caron, Ceglarek, Goros, Guan, Huang, Kaabiaa, Kappas, Ke, Magnisali, Peitzsch, Ray, Schioler, Shao, Stanczyk, Taieb, Thomas, Wong, You   +20 more
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

FEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson, Robert Gustafsson Westergren, Ingrid Almlöf, Ann‐Sofie Jemth, Martin Scobie, Ulrika Warpman Berglund, Thomas Helleday, Pål Stenmark   +7 more
wiley   +1 more source

A new method for determination of fluoride ion in commodity tea by ion-exclusion chromatography

CyTA - Journal of Food, 2018
Due to the effect of interfering ion, the content of fluoride ion in tea brew, detected by ion-exchange chromatography, was markedly higher than ion-selective electrode.
Lili Zhou, Huaiping Li, Shanrong Ye, Heping Tan   +3 more
doaj   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Experimental Method and Application of Rapid and Continuous Extraction of Reduced Inorganic Sulfur from Sediments

Yankuang ceshi, 2023
BACKGROUND Sulfur is an active element with multiple chemical forms, which plays a vital role in the regulation of redox chemistry. Reduced inorganic sulfur (RIS) including acid volatile sulfur (AVS), elemental sulfur (ES) and pyrite sulfur (CRS) is the ...
MAO Changping, DU Suming, JIA Zhimin, YU Gang, WANG Yao, RAO Wenbo   +5 more
doaj   +1 more source

Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry [PDF]

, 2005
A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described. Fenbuconazole is used as an internal standard.
Boyd, Denning, Dooley, Gage, Glasmacher, Hyland, Johnson, Keevil, Ozawa, Pennick, Potoski, Roffey, Stopher, Trifilio, Vogeser, Vogeser, Vogeser   +16 more
core   +1 more source

Combined Liquid Chromatography-Infrared Ion Spectroscopy for Identification of Regioisomeric Drug Metabolites

Analytical Chemistry, 2017
High-performance liquid chromatography was used in combination with infrared ion spectroscopy for the identification of positional isomers of hydroxy-atorvastatins, the primary metabolites of the drug atorvastatin.
J. Martens, Valérie Koppen, G. Berden, F. Cuyckens, J. Oomens   +4 more
semanticscholar   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

FEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter, James Larson, Monika Tokmina‐Lukaszewska, Jin Xiong, Jared Green, Yisong Guo, William E. Broderick, Brian Bothner, Joan B. Broderick   +8 more
wiley   +1 more source

Determination of Sodium, Potassium, and Magnesium as Sulfate Salts in Oral Preparations Using Ion Chromatography and Conductivity Detection

Separations, 2023
An ion chromatography technique with conductivity detection was selected as an analytical tool for the simultaneous indirect determination of sodium sulfate, potassium sulfate, and magnesium sulfate via their respective cations.
Suresh Reddy Yelampalli, Kumaraswamy Gandla, Konatham Teja Kumar Reddy, Adel Ehab Ibrahim, Sami El Deeb   +4 more
doaj   +1 more source