Results 111 to 120 of about 2,015,688 (302)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Ion beam sputtering of fluoropolymers [PDF]

Ion beam sputter processing rates as well as pertinent characteristics of etched targets and films are described. An argon ion beam source was used to sputter etch and deposit the fluoropolymers PTFE, FEP, and CTFE.
Sovey, J. S.
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

In-situ Monitoring of Temperature and Voltage in Lithium-Ion Battery by Embedded Flexible Micro Temperature and Voltage Sensor

International Journal of Electrochemical Science, 2013
Lithium-ion batteries are utilized in mobile phones, personal digital assistants (PDA), 3C products and electric vehicles. Batteries must be rapidly chargeable. They discharge in devices.
Chi-Yuan Lee, Shuo-Jen Lee, Yi-Ho Chen, Ming-Yu Chung, Kuo-Chang Han, Yu-Ming Chang, Ming-Shao Tang   +6 more
doaj   +1 more source

Modulating the phase transition temperature of giant magnetocaloric thin films by ion irradiation

, 2017
Magnetic refrigeration based on the magnetocaloric effect at room temperature is one of the most attractive alternative to the current gas compression/expansion method routinely employed.
Carrétéro, C, Cervera, S., Garcia, V, Hidki, S, Jacquet, E, Lamour, E, Lévy, A, Macé, S, Marangolo, M, Prigent, C, Rozet, J, Steydli, S, Trassinelli, M, Vernhet, D   +13 more
core   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Preparation of atomically clean and flat Si(100) surfaces by low-energy ion sputtering and low-temperature annealing

, 2003
Si(100) surfaces were prepared by wet-chemical etching followed by 0.3-1.5keV Ar ion sputtering, either at elevated or room temperature. After a brief anneal under ultrahigh vacuum conditions, the resulting surfaces were examined by scanning tunneling ...
Al-Bayati, Al-Bayati, Arima, Bean, Bedrossian, Bedrossian, Chey, Feil, Gossmann, Henderson, Higashi, Huang, Ishizaka, J.-Y. Ji, J.C. Kim, J.R. Tucker, J.S. Kline, Joyce, Lee, Morita, Neuwald, Shen, Swartzentruber, T.-C. Shen, Usuda, Zandvliet   +25 more
core   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Stability optimization based on high-resolution spatial thermal distribution of a single 174Yb+ ion

Shenzhen Daxue xuebao. Ligong ban
Trapped ion systems play a vital role in fields such as quantum information processing and optical frequency standards. Low-energy, highly stable trapped ions enable precise quantum manipulation and significantly reduce Doppler effect.
NIU Haipo, ZHENG Pengcheng, HUANG Qiyin, HUANG Zerui, ZHANG Songqian, LIU Peiliang   +5 more
doaj   +1 more source