Results 21 to 30 of about 42,160 (245)

Multiple Bactericidal Mechanisms of the Zinc Ionophore PBT2

mSphere, 2020
Globally, more antimicrobials are used in food-producing animals than in humans, and the extensive use of medically important human antimicrobials poses a significant public health threat in the face of rising antimicrobial resistance (AMR).
Nichaela Harbison-Price, Scott A. Ferguson, Adam Heikal, George Taiaroa, Kiel Hards, Yoshio Nakatani, David Rennison, Margaret A. Brimble, Ibrahim M. El-Deeb, Lisa Bohlmann, Christopher A. McDevitt, Mark von Itzstein, Mark J. Walker, Gregory M. Cook   +13 more
doaj   +1 more source

Development and Optimization of a Highly Sensitive Sensor to Quinine-Based Saltiness Enhancement Effect

Sensors, 2023
The saltiness enhancement effect can be produced by adding specific substances to dietary salt (sodium chloride). This effect has been used in salt-reduced food to help people forge healthy eating habits.
Yifei Jing, Kentaro Watanabe, Tatsukichi Watanabe, Shunsuke Kimura, Kiyoshi Toko   +4 more
doaj   +1 more source

Matrix-free calcium in isolated chromaffin vesicles [PDF]

, 1985
Isolated secretory vesicles from bovine adrenal medulla contain 80 nmol of Ca2+ and 25 nmol of Mg2+ per milligram of protein. As determined with a Ca2+-selective electrode, a further accumulation of about 160 nmol of Ca2+/mg of protein can be attained ...
Bashford L. C., Borowitz J. L., Borowitz J. L., Bradford M., Coll K. E., Debono M., Department of Biochemistry, Flodgaard H., Gratzl M., Grinstein S., Hansford R. G., Johnson R. G., Joseph S. K., Knight D. E., Krieger-Brauer H., Krieger-Brauer H., Krieger-Brauer H., Lowry O. H., MacLennan D. M., Nordmann J. J., Pfeiffer D. R., Pfeiffer D. R., Phillips J. H., Phillips J. H., Pollard B., Pollard B., Ravazzola M., Reed P. W., Reed P. W., Reinhart P. H., Saermark T., Saermark T., Serck-Hanssen G., Sillen L. G., Simon W., Wada A.   +35 more
core   +2 more sources

Synthesis of a ditopic homooxacalix[3]arene for fluorescence enhanced detection of heavy and transition metal ions [PDF]

, 2015
A pyrene-appended ratiometric fluorescent chemosensor L based on a synthetic approach of insulating the fluorophore from the ionophore by a specific molecular spacer has been synthesised and characterised.
Jin, Cheng-Cheng, Mou, Lan, Ni, Xin-Long, Redshaw, Carl, Wu, Yanan, Yamato, Takehiko   +5 more
core   +2 more sources

Calcium signalling links MYC to NUAK1 [PDF]

, 2018
NUAK1 is a member of the AMPK-related family of kinases. Recent evidence suggests that NUAK1 is an important regulator of cell adhesion and migration, cellular and organismal metabolism, and regulation of TAU stability.
Hedley, A,, Knight, J.R., Monteverde, T., Murphy, D.J., Sansom, O.J., Tait-Mulder, J.   +5 more
core   +1 more source

Effects of Monovalent and Divalent Cations on Ca2+ Fluxes Across Chromaffin Secretory Membrane Vesicles [PDF]

, 1983
: Bovine chromaffin secretory vesicle ghosts loaded with Na+ were found to take up Ca2+ when incubated in K+ media or in sucrose media containing micromolar concentrations of free Ca2+. Li+- or choline+loaded ghosts did not take up Ca2+.
Baker P. F., Borle A. B., Carafoli E., Flodgaard H., Goldstone T. P., Heidemarie I. Krieger-Brauer, Kostron H., Lowry O. H., Manfred Gratzl, Phillips J. H., Reed K. C., Saermark T., Sandeaux R., Sillen L. G.   +13 more
core   +1 more source

The Ionophores CCCP and Gramicidin but Not Nigericin Inhibit Trypanosoma brucei Aquaglyceroporins at Neutral pH

Cells, 2020
Human African trypanosomiasis (HAT) is caused by Trypanosoma brucei parasites. The T. brucei aquaglyceroporin isoform 2, TbAQP2, has been linked to the uptake of pentamidine.
Lea Madlen Petersen, Eric Beitz
doaj   +1 more source

Proton Motive Force-Dependent Hoechst 33342 Transport by the ABC Transporter LmrA of Lactococcus lactis [PDF]

, 2005
The fluorescent compound Hoechst 33342 is a substrate for many multidrug resistance (MDR) transporters and is widely used to characterize their transport activity.
Abbreviations ABC, Chen M., Doerrler W. T., Ecker G. F., Gajic O., Haugland R. P., Higuchi R., Ketchum C. J., Kuipers O. P., Lalande M. E., Lanzetta P. A., Lewinson O., Linnett P. E., Lubelski J., Lubelski J., Margolles A., Mazurkiewicz P., Orelle C., Paternostre M. T., Poelarends G. J., Putman M., Sakamoto K., Sambrook J., Shapiro A. B., Shapiro A. B., Shapiro A. B., Shapiro A. B., Sharma S., Steinfels E., Urbatsch I. L., van Veen H. W., van Veen H. W., van Veen H. W., Venter H., Viitanen P., Yu J. L.   +35 more
core   +2 more sources

Duramycin-induced calcium release in cancer cells [PDF]

, 2015
Introduction: Duramycin through binding with phosphatidylethanolamine (PE) has shown potential to be an effective anti-tumour agent. However its mode of action in relation to tumour cells is not fully understood.
Broughton, Laura J., Crow, Chris, Madden, Leigh A., Maraveyas, Anthony   +3 more
core   +1 more source

Effects of a Blend of Live Yeast and Organic Minerals as an Alternative to Monensin on Intake, Digestibility, Performance and Beef Quality of Nellore Bulls Finished on Pasture with High Concentrate Supplementation

Agriculture, 2023
Effects of a blend of live yeast and organic minerals as an alternative to monensin and inorganic trace minerals for beef cattle finished on pasture with high concentrate supplementation, on growth performance, intake, digestibility, liver trace mineral ...
Maxwelder Santos Soares, Luis Henrique Curcino Batista, Ivanna Moraes Oliveira, Hugo Aparecido Silveira Issa, Iorrano Andrade Cidrini, Igor Machado Ferreira, Luiz Fernando Costa e Silva, Anne Koontz, Vaughn Holder, Gustavo Rezende Siqueira, Flávio Dutra de Resende   +10 more
doaj   +1 more source