Results 51 to 60 of about 2,694 (167)

Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

Journal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia, Medha Noopur, Ishana Bhattacharya, Bhaskar Chandra Sahoo, Mritunjay Kasera, Naga Jyothi Pullagurla, Smritikana Dutta, Guizhen Liu, Gabriel Schaaf, Henning Jessen, Debabrata Laha, Souvik Bhattacharjee, Saikat Bhattacharjee   +12 more
wiley   +1 more source

Microbial degradation of myo-inositol hexakisphosphate (IP6): specificity, kinetics, and simulation [PDF]

3 Biotech, 2018
Microbial degradation of myo-inositol hexakisphosphate (IP6) is crucial to deal with nutritional problems in monogastric animals as well as to prevent environmental phosphate pollution. The present study deals with the degradation of IP6 by microorganisms such as Sporosarcina spp.
Paul Priyodip, Seetharaman Balaji
openaire   +2 more sources

Vibrio type III effector VPA1380 is related to the cysteine protease domain of large bacterial toxins. [PDF]

PLoS ONE, 2014
Vibrio parahaemolyticus is a Gram-negative halophilic bacterium and one of the leading causes of food-borne gastroenteritis. Its genome harbors two Type III Secretion Systems (T3SS1 and T3SS2), but only T3SS2 is required for enterotoxicity seen in animal
Thomas Calder, Lisa N Kinch, Jessie Fernandez, Dor Salomon, Nick V Grishin, Kim Orth   +5 more
doaj   +1 more source

QTL Mapping of Several Seed Quality Traits in the DH Population NPZ06 × NPZ09 (Brassica napus L.) for Marker‐Assisted Selection

Plant Breeding, EarlyView.
ABSTRACT Enhancing nutritional quality of oilseed rape requires deeper insight into the genetic control of seed quality traits. This study analysed the effect of varying soil phosphorus (P) levels on seed quality traits in the hybrid cultivar Architect. NIRS and laboratory methods were used to quantify total seed P and phytic acid (IP6) content.
Jasmin Vettel, Markus Rodehutscord, Christian Möllers   +2 more
wiley   +1 more source

Phytic Acid Protects against 6-Hydroxydopamine-Induced Dopaminergic Neuron Apoptosis in Normal and Iron Excess Conditions in a Cell Culture Model

Parkinson's Disease, 2011
Iron may play an important role in Parkinson's disease (PD) since it can induce oxidative stress-dependent neurodegeneration. The objective of this study was to determine whether the iron chelator, phytic acid (IP6) can protect against 6-hydroxydopamine-
Qi Xu, Anumantha G. Kanthasamy, Manju B. Reddy   +2 more
doaj   +1 more source

Phytic Acid Decreases Oxidative Stress and Intestinal Lesions Induced by Fumonisin B1 and Deoxynivalenol in Intestinal Explants of Pigs

Toxins, 2019
The purpose of the present study was to investigate the effects of phytic acid (IP6) on morphological and immunohistochemical parameters and oxidative stress response in intestinal explants of pigs exposed to fumonisin B1 (FB1) and/or deoxynivalenol (DON)
Elisângela O. da Silva, Juliana R. Gerez, Miriam S. N. Hohmann, Waldiceu A. Verri, Ana Paula F. R. L. Bracarense   +4 more
doaj   +1 more source

Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP6, resulting in differentially altered cytoplasmic mRNA expression and specific cell defect. [PDF]

PLoS ONE, 2018
DBP5, also known as DDX19, GLE1 and inositol hexakisphosphate (IP6) function in messenger RNA (mRNA) export at the cytoplasmic surface of the nuclear pore complex in eukaryotic cells.
Masumi Okamura, Yasutaka Yamanaka, Maki Shigemoto, Yuya Kitadani, Yuhko Kobayashi, Taiho Kambe, Masaya Nagao, Issei Kobayashi, Katsuzumi Okumura, Seiji Masuda   +9 more
doaj   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

Inositol hexakisphosphate is required for Integrator function

Nature Communications, 2022
Integrator is a multi-subunit protein complex with roles in noncoding RNA 3′-end processing and mRNA transcription attenuation. Here, the authors reveal a conserved binding site for IP6 in the Integrator cleavage module and show that IP6 binding is ...
Min-Han Lin, Madeline K. Jensen, Nathan D. Elrod, Kai-Lieh Huang, Kevin A. Welle, Eric J. Wagner, Liang Tong   +6 more
doaj   +1 more source