Results 121 to 130 of about 83,328 (323)

Selecting first-line immunotherapy in advanced melanoma: Current evidence on efficacy across diverse patient populations

EJC Skin Cancer
Immunotherapy has dramatically changed the outcome for patients with advanced melanoma, with significant improvements in overall survival and potential cure for some.
Sophia Kreft, Tommaso Bosetti, Rebecca Lee, Paul Lorigan   +3 more
doaj   +1 more source

Flare-Up of Rheumatoid Arthritis by Anti-CTLA-4 Antibody but Not by Anti-PD1 Therapy in a Patient with Metastatic Melanoma

Case Reports in Dermatology, 2017
A 47-year-old female patient with rheumatoid arthritis (RA) treated with methotrexate, was diagnosed with metastatic melanoma. After surgical removal of the tumor, the patient started treatment with ipilimumab while methotrexate was stopped.
Nicoletta F. Jaberg-Bentele, Michael Kunz, Shatha Abuhammad, Reinhard Dummer   +3 more
doaj   +1 more source

MON-290 Ipilimumab Immune-Related ACTH Deficiency Is of Acute Onset and Severe [PDF]

, 2020
Khyatisha Seejore, Marilena Giannoudi, Djoah Osborn, Julie Lynch, Elaine Dunwoodie, Jane Hook, Maria Marples, Robert Murray   +7 more
openalex   +1 more source

Papillary renal cell carcinoma with high‐ABCC2 shows an immune‐evasive profile associated with favorable response to immunotherapy

The Journal of Pathology, EarlyView.
Abstract The use of immune checkpoint inhibitors is a promising therapeutic strategy for metastatic papillary renal cell carcinoma (PRCC); however, predictive biomarkers remain limited. PRCCs with high ABCC2 expression represent an aggressive subset frequently associated with metastasis.
Vincent Francis Castillo, Abraam Zakhary, Fabio Rotondo, Caterina Di Ciano‐Oliveira, Malek Hamdani, Emelyn Adona, Theodorus van der Kwast, Kiril Trpkov, Rola Saleeb   +8 more
wiley   +1 more source

Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Uveal melanoma is the most common malignant primary intraocular tumor in adults, associated with high mortality. Pediatric uveal melanoma generally has a more favorable course. However, when metastasis occurs, therapeutic options are limited.
Pia Tüller, Tobias Kiefer, Leyla Jabbarli, Kyriaki Papaioannou, Kathrin Schramm, Nicole Barwinski, Stefan Schönberger, Ines B. Brecht, Dominik T. Schneider, Elisabeth Livingstone, Lisa Zimmer, Karen Fischhuber, Andreas Junker, Saskia Ting, Cordula Kiewert, Sophia Göricke, Nikolaos Bechrakis, Eva Biewald, Petra Ketteler   +18 more
wiley   +1 more source

Late-Onset Inflammatory Bowel Disease-Like Syndrome after Ipilimumab Therapy: A Case Report

Case Reports in Oncology, 2017
Background: Antitumor immunotherapy has become a major player in cancer therapy. Ipilimumab is a humanized monoclonal antibody against the cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), an important downregulator of T-cell activation.
Reem Akel, Bilal Anouti, Arafat Tfayli
doaj   +1 more source

Analogue peptides for the immunotherapy of human acute myeloid leukemia [PDF]

, 2015
Accepted manuscript. The final publication is available at: http://link.springer.com/article/10.1007%2Fs00262-015-1762-9The use of peptide vaccines, enhanced by adjuvants, has shown some efficacy in clinical trials.
A Driessche Van, A Gros, A Scardino, A Serrano, A Sevko, A Snyder, A Tsuboi, AB Bakker, Aleksandrs Malinovskis, Andrew Mead, AT Cheuk, AW Purcell, B Engels, B Falini, B Maecker, B Maecker, B Uttenthal, BA Guinn, BA Guinn, Barbara-ann Guinn, C Chaise, C Maccalli, CL Slingluff Jr, D Cilloni, D Mason, DA Gross, DE Speiser, DH Chang, DJ Schwartzentruber, E Estey, E Romano, F Ghiringhelli, FS Hodi, G Khan, H Kobayashi, H Ohminami, HJ Kolb, HJ Stauss, I Bellantuono, J Bae, J Bae, J Fourcade, J Greiner, J Greiner, J Kronke, J Pinilla-Ibarz, J Pinilla-Ibarz, JH Sampson, JJ Molldrem, JL Chen, JL Chen, JN Kochenderfer, JS Ko, JW Wells, K Inoue, K Inoue, K Rezvani, K Rezvani, KM Zirlik, L Chan, L Fong, L Gao, LV Ly, M Harndahl, M Kapp, M Subklewe, MA Cheever, MG Warnock, MM Gubin, MR Parkhurst, MS Bijker, N Hardwick, Nicola R. Hardwick, O Christensen, O Hamid, P Brossart, P Bruggen van der, P Keskinen, PG Maslak, PG Maslak, R Cibotti, RA Padua, RF Schlenk, RJ May, S Frankild, S Hofmann, S Narayan, S Ochsenreither, S Pascolo, S Suekane, S Walter, SH Burg van der, SK Singh, SL Topalian, SP Adams, Susanne Hofmann, T Lovgren, U Keilholz, U Sahin, V Bhardwaj, WS Meng, Y Oka, Z Trajanoski   +102 more
core   +2 more sources

Supplementary fig 1 from A Phase II Study of Allogeneic GM-CSF–Transfected Pancreatic Tumor Vaccine (GVAX) with Ipilimumab as Maintenance Treatment for Metastatic Pancreatic Cancer

, 2023
Annie A. Wu, Katherine M. Bever, Won Jin Ho, Elana J. Fertig, Nan Niu, Lei Zheng, Rose Parkinson, Jennifer N. Durham, Beth Onners, Anna Ferguson, Cara Wilt, Andrew H. Ko, Andrea Wang‐Gillam, Daniel A. Laheru, Robert A. Anders, Elizabeth D. Thompson, Elizabeth A. Sugar, Elizabeth M. Jaffee, Dung T. Le   +18 more
openalex   +1 more source

Renal cell carcinoma with atypical omental metastasis: A case report and literature review

UroPrecision, EarlyView.
Abstract Background Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, with common metastatic sites including the lungs, bones, liver, and brain. Omental metastasis is exceedingly rare and usually occurs postoperatively. Fumarate hydratase‐deficient (FH‐deficient) RCC, a recently classified and highly aggressive subtype of ...
Andrew Jing, Zachary Guo, Katherine Wu, Wei Wang, James Jing   +4 more
wiley   +1 more source

C‐Reactive Protein Kinetics as Prognostic Biomarkers in Stage IV‐Melanoma Treated With Immune Checkpoint Inhibitors in the Japanese Population: A Single‐Center, Retrospective Cohort Study

The Journal of Dermatology, EarlyView.
ABSTRACT Malignant melanoma is an aggressive form of skin cancer with variable outcomes in response to immunotherapy. Although immune checkpoint inhibitors have improved survival in patients with advanced melanoma, predicting which patients will benefit from treatment remains a major clinical challenge. This study aimed to evaluate the prognostic value
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source