Results 51 to 60 of about 187,622 (243)
Frontiers in Drug Safety and Regulation, 2023 Introduction: The antimalarials chloroquine and hydroxychloroquine have been used for several decades in treating malaria and some autoimmune diseases—mainly rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)—with excellent efficacy and ...
Pedro Santos-Moreno +8 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Pemahaman Guru IPS Terhadap Konsep Keruangan Pada Kompetensi Dasar Mata Pelajaran IPS [PDF]
, 2022 Konsep keruangan merupakan bingkai dari pembelajaran IPS yang didesain melalui kompetensi dasar yang telah disusun dalam kurikulum pembelajaran IPS pada jenjang SMP.
Muhammad Ilyas Marzuqi +1 more
core +1 more source
Slow death of excellence: Eulogy of central institute of psychiatry, Ranchi
Indian Journal of PsychiatryThe Central Institute of Psychiatry (CIP), Ranchi, has been a cornerstone of Indian psychiatry since its founding in 1918, pioneering therapies, psychopharmacology, child and community mental health services, and training generations of psychiatrists. It
Gulesh Kumar, Amrit Pattojoshi
doaj +1 more source
Pendekatan Heutagogi: Sebuah alternatif dalam pembelajaran IPS pada masa pandemi Covid-19
Jurnal Teori dan Praksis Pembelajaran IPS, 2021 Abstrak Pembelajaran IPS memiliki orientasi menjadikan peserta didik sebagai aktor sosial yang memiliki kecerdasan sosial. Penulisan artikel ini memiliki tujuan untuk memberikan gagasan pada pembelajaran IPS di masa pandemi dengan pendekatan heutagogi ...
Danan Tricahyono
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain [PDF]
, 2010 Background: IPS-1/MAVS/VISA/Cardif is an adaptor protein that plays a crucial role in the induction of interferons in response to viral infection. In the initial stage of the intracellular antiviral response two RNA helicases, retinoic acid inducible ...
Taylor, Garry L. +2 more
core +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Suv4-20h abrogation enhances telomere elongation during reprogramming and confers a higher tumorigenic potential to iPS cells [PDF]
, 2011 Reprogramming of adult differentiated cells to induced pluripotent stem cells (iPS) cells has been achieved by over-expression of specific transcription factors.
Maria A. Blasco +13 more
core +1 more source
Building Students' Learning Experience in Online Learning During Pandemic
Al-Ishlah: Jurnal Pendidikan, 2021 The practice of online learning during a pandemic is ideally able to provide independent learning for students. However, what happens is the loss of a meaningful learning experience.
Syaharuddin Syaharuddin +4 more
doaj +1 more source