Results 11 to 20 of about 102,759 (307)

Lucky iPSCs [PDF]

open access: yesGenome Biology, 2014
AbstractThe probabilistic behavior of direct induction of pluripotency has been a subject of intense research interest. Here we discuss recently published reports on this topic.
Zviran, Asaf, Hanna, Jacob H
openaire   +2 more sources

CiRA iPSC seed stocks (CiRA's iPSC Stock Project)

open access: yesStem Cell Research, 2021
In Japan, induced pluripotent stem cell (iPSC) Stock Project has started from 2013. The goal of the Project is to manufacture and release clinical-grade HLA homozygous iPSC lines that can cover almost the entire of Japanese population. We show the summary of the cell lines distributed, test results for quality control and future plans.
Tadaaki Hanatani, Naoko Takasu
openaire   +3 more sources

Natural disasters and COVID-19: health worker preparedness and response [PDF]

open access: yesE3S Web of Conferences, 2021
The purpose of this study was to determine the preparedness of health workers individually and in the workplace to deal with natural disasters during COVID-19.
Wahyuni Dewi   +4 more
doaj   +1 more source

Generation of donor organs in chimeric animals via blastocyst complementation

open access: yesВавиловский журнал генетики и селекции, 2020
The lack of organs for transplantation is an important problem in medicine today. The growth of organs in chimeric animals may be the solution of this.
T. I. Babochkina   +2 more
doaj   +1 more source

Determination of tsunami run-up and golden time in the megathrust subduction zone of the sunda strait segment [PDF]

open access: yesE3S Web of Conferences, 2021
The Indonesian Disaster Data and Information Management Database state that the tsunami in the Megathrust Subduction Zone of the Sunda Strait Segment is a disaster threat with high impact and loss of life every time it occurs.
Sarikanti Ponangsera Iko   +3 more
doaj   +1 more source

Pluripotent Stem Cell-Based Models: A Peephole into Virus Infections during Early Pregnancy

open access: yesCells, 2020
The rubella virus (RV) was the first virus shown to be teratogenic in humans. The wealth of data on the clinical symptoms associated with congenital rubella syndrome is in stark contrast to an incomplete understanding of the forces leading to the ...
Claudia Claus   +2 more
doaj   +1 more source

STAT3 modulates reprogramming efficiency of human somatic cells; insights from autosomal dominant Hyper IgE syndrome caused by STAT3 mutations

open access: yesBiology Open, 2020
Human induced pluripotent stem cell (iPSC) technology has opened exciting opportunities for stem-cell-based therapy. However, its wide adoption is precluded by several challenges including low reprogramming efficiency and potential for malignant ...
Zhen Yu   +11 more
doaj   +1 more source

mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells

open access: yesDisease Models & Mechanisms, 2019
Bi-allelic GBA1 mutations cause Gaucher's disease (GD), the most common lysosomal storage disorder. Neuronopathic manifestations in GD include neurodegeneration, which can be severe and rapidly progressive.
Robert A. Brown   +8 more
doaj   +1 more source

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

open access: yes, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E   +4 more
core   +1 more source

Extracellular Vesicles Derived from Induced Pluripotent Stem Cells Promote Renoprotection in Acute Kidney Injury Model

open access: yesCells, 2020
Induced pluripotent stem cells (iPSC) have been the focus of several studies due to their wide range of application, including in cellular therapy. The use of iPSC in regenerative medicine is limited by their tumorigenic potential. Extracellular vesicles
Federica Collino   +12 more
doaj   +1 more source

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