Model system dynamics potential impact of disasters due to the re-period of the October 25th, 2010 earthquake in the Mentawai Islands [PDF]
Geographically, the Mentawai Islands Regency has a territorial boundary with the sea. The north side is the Siberut Strait, the south side is bordered by the Indian Ocean, the east side is bordered by the Mentawai Strait, and the west side is bordered by
Aprilyanto +3 more
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Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia +17 more
core +1 more source
When Fibroblasts MET iPSCs [PDF]
Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming ...
Polo, Jose M., Hochedlinger, Konrad
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Pentahelix synergity natural and non-natural disaster management in Pidie Jaya District Aceh Province to support national security [PDF]
Geographically, Indonesia is located on disaster prone area. Natural disasters such as earthquakes, tsunamis, floods, landslides, volcanic eruptions and non-natural disaster such as Covid-19 Pandemic often occur in various places in Indonesia including ...
Yulianto Sugeng +3 more
doaj +1 more source
The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia [PDF]
© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the ...
A.M. Lavoie +45 more
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Phenotyping Neurodegeneration in Human iPSCs [PDF]
Induced pluripotent stem cell (iPSC) technology holds promise for modeling neurodegenerative diseases. Traditional approaches for disease modeling using animal and cellular models require knowledge of disease mutations. However, many patients with neurodegenerative diseases do not have a known genetic cause.
Li, Jonathan, Fraenkel, Ernest
openaire +4 more sources
Induced Stem Cells as a Novel Multiple Sclerosis Therapy. [PDF]
Stem cell replacement is providing hope for many degenerative diseases that lack effective therapeutic methods including multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. Transplantation of neural stem cells or
Guan, Yang-Tai +3 more
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Overcoming iPSC Obstacles [PDF]
We asked six leaders in the reprogramming field to share their views on remaining gaps in our scientific understanding of iPSCs that will need to be addressed to achieve their clinical promise. Their insights echo many issues raised in the Review by Tapia and Scholer in this issue.
Wernig, M., Götz, M., Eto, K.
openaire +3 more sources
Human pluripotent stem cells offer a limitless source of cells for regenerative medicine. They are also highly valuable as tools to study development and pathologies or as cellular substrates to screen and test new drugs.
Eddy Quelennec +5 more
doaj +1 more source
Earthquake and tsunami potential levels in Sulawesi (lesson learned earthquake West Sulawesi) [PDF]
Earthquake and tsunami disasters always bring negative impacts and losses for humans. The high frequency of earthquake disasters in Sulawesi and the massive impact of destruction and damage to infrastructure, loss of homes and property, and death of ...
Khoirudin Apriyadi Rio +3 more
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