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Institute for Quality and Efficiency in Health Care: Germany [PDF]

open access: yes, 2009
Provides an overview of evidence-based policy making in the German healthcare system. Focuses on the Institute for Quality and Efficiency in Health Care, which evaluates comparative effectiveness of drugs and medical services for decisions on ...
Mona Nasser, Peter Sawicki
core  

Höchstmöglicher ESMO-Wert vs. kein Zusatzznutzen

open access: yesMonitor Versorgungsforschung
Im Titelinterview mit „Monitor Versorgungsforschung“ (02/25) ging Dr. med. Thomas Kaiser, Institutsleiter des IQWiG, kurz auf die Nutzenbewertung des Wirkstoffs Pembrolizumab und des MSD-Arznemittels „Keytruda“ ein (1): Auf die Frage „Wie kommt es, dass ...
Peter Stegmaier
doaj   +1 more source

Quality ratings of reviews in overviews: a comparison of reviews with and without dual (co-)authorship

open access: yesSystematic Reviews, 2018
Background Previous research shows that many authors of Cochrane overviews were also involved in some of the included systematic reviews (SRs). This type of dual (co-)authorship (DCA) may be a conflict of interest and a potential source of bias.
Dawid Pieper   +3 more
doaj   +1 more source

Tonsillectomy versus tonsillotomy for recurrent acute tonsillitis in children and adults (TOTO): study protocol for a randomized non-inferiority trial

open access: yesTrials, 2021
Background Tonsillectomy is one of the most frequently performed surgeries in children and young adults worldwide. For decades, tonsillectomy was the surgical treatment of choice for recurrent acute tonsillitis. Tonsillotomy was used in some countries as
Orlando Guntinas-Lichius   +4 more
doaj   +1 more source

Published and unpublished evidence in coverage decision-making for pharmaceuticals in Europe: existing approaches and way forward [PDF]

open access: yes, 2016
List of regulatory documents organized per country and list of publications.
Alexandra Nolting   +4 more
core   +7 more sources

Patients’ preferences in periodontal disease treatment elicited alongside an IQWiG benefit assessment: a feasibility study

open access: yesPatient Preference and Adherence, 2018
Background and purpose The German Institute for Quality and Efficiency in Health Care (IQWiG) previously tested two preference elicitation methods in pilot projects and regarded them as generally feasible for prioritizing outcome-specific results of ...
Vera Vennedey   +9 more
semanticscholar   +1 more source

Event‐free survival and complete response rate as surrogate endpoints for overall survival in high‐risk non–muscle‐invasive bladder cancer: A meta‐analysis of bacillus Calmette‐Guérin—naive or —remote cases

open access: yesCancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Event‐free survival (EFS) and complete response rate (CRR) are recommended as primary endpoints in bladder cancer trials to enable timely assessment of therapeutic benefit. However, their surrogacy relationship with overall survival (OS) in high‐risk non–muscle‐invasive bladder cancer (HR NMIBC) remains unclear.
Rituparna Bhattacharya   +8 more
wiley   +1 more source

Anwendungsbegleitende Datenerhebungen für die Nutzenbewertung von Arzneimitteln in Deutschland: Warum, wann und wie?

open access: yesGMS Medizinische Informatik, Biometrie und Epidemiologie
For newly authorised medicinal products with new active substances, a benefit assessment is carried out at the time of their market access in Germany. The subject of this assessment is the question of the additional benefit of the new active substance ...
Kaiser, Thomas, Vervölgy, Volker
doaj   +1 more source

Cost recommendation under uncertainty in IQWiG’s efficiency frontier framework [PDF]

open access: yes, 2016
Background: The National Institute for Quality and Efficiency in Health Care (IQWiG) employs an efficiency frontier (EF) framework to facilitate setting maximum reimbursable prices for new interventions.
Al, Maiwenn J.   +3 more
core   +2 more sources

Cost‐Effectiveness Analysis of Risky Health Interventions: Moving Beyond Risk Neutrality

open access: yesRatio, Volume 38, Issue 4, Page 219-227, December 2025.
ABSTRACT Cost‐effectiveness analysis for health interventions is traditionally conducted in a risk‐neutral way, insensitive to risk attitudes in the population, which are potentially non‐neutral. While the standard outcome metric of quality‐adjusted life years (QALYs) aims to be deferential to people's valuations of health states, cost‐effectiveness ...
Johanna Thoma
wiley   +1 more source

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