Results 71 to 80 of about 5,242 (246)

Opportunities to improve the adoption of health-related quality of life evidence as part of the French Health Technology Assessment process

open access: yesHealth Research Policy and Systems, 2023
Objectives Patient’s health-related quality of life (HRQoL) is an important outcome measure that is considered by many payers and health technology assessment (HTA) bodies in the evaluation of treatments.
Hugo Larose   +10 more
doaj   +1 more source

Rationalisierung und Wettbewerb im Arzneimittelmarkt [PDF]

open access: yes, 2012
Rationalisierungsmaßnahmen sind bei steigenden Ausgaben in einem vor allem durch Umlagen finanzierten Gesundheitssystem wichtige Mittel zur Erreichung einer effizienten Produktion und Allokation der Ressourcen.
Herr, Annika
core  

Enhancing Drug Development for Paediatric Pulmonary Hypertension—An Integrative Perspective

open access: yesPulmonary Circulation, Volume 15, Issue 3, July 2025.
ABSTRACT As with adult pulmonary hypertension (PH), high morbidity and mortality persist with diverse types of paediatric PH. Despite major advances in pharmacologic therapies based on extensive studies in adult PH, few drugs have been comprehensively studied in neonates, infants, and children, leaving current paediatric PH care largely dependent on ...
Steven H. Abman   +14 more
wiley   +1 more source

„Stärkerer Fokus auf die Methoden der Studiendurchführung“

open access: yesMonitor Versorgungsforschung
Nach Prof. Dr. med. Peter Sawicki (2004 bis 2009) und Prof. Dr. med. Jürgen Windeler (2010 bis März 2023) ist seit April 2023 Dr. med. Thomas Kaiser der dritte Leiter des Instituts für Qualität und Wirtschaftlichkeit im Gesundheitswesen (IQWiG).
Dr. med. Thomas Kaiser, Peter Stegmaier
doaj   +1 more source

Cost-effectiveness of managing cavitated primary molar caries lesions:A randomized trial in Germany [PDF]

open access: yes, 2018
The Hall Technique (HT), Non-Restorative Cavity Control (NRCC) and conventional carious tissue removal and restoration (CR) are strategies for managing cavitated caries lesions in primary molars.
Innes, Nicola   +6 more
core   +2 more sources

Hazards Constitute Key Quantities for Analyzing, Interpreting and Understanding Time‐to‐Event Data

open access: yesBiometrical Journal, Volume 67, Issue 3, June 2025.
ABSTRACT Censoring makes time‐to‐event data special and requires customized statistical techniques. Survival and event history analysis therefore builds on hazards as the identifiable quantities in the presence of rather general censoring schemes. The reason is that hazards are conditional quantities, given previous survival, which enables estimation ...
Jan Beyersmann   +2 more
wiley   +1 more source

A proportional rule for setting reimbursement prices of new drugs and its mathematical consistency

open access: yesBMC Health Services Research, 2020
Background Value-based pricing (VBP) of new drugs has been suggested both as a way to control health expenditures and to maximize health benefits based on the available resources. The purpose of this work is to present a simple mathematical proof showing
Afschin Gandjour
doaj   +1 more source

Reply to: Letter to the Editor on the Paper: “Do the Clinical Practice Guidelines for Pediatric Dentistry Meet the Quality Standards?”

open access: yes
International Journal of Paediatric Dentistry, Volume 35, Issue 6, Page 1023-1025, November 2025.
Rokaia Ahmed Elagami   +7 more
wiley   +1 more source

Antero‐Lateral Subthalamic Nucleus Theta Stimulation Improves Verbal Fluency in Parkinson's Disease

open access: yesMovement Disorders, Volume 40, Issue 6, Page 1195-1199, June 2025.
Abstract Objective Low‐frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been associated with positive effects on verbal fluency (VF) in patients with Parkinson's disease. This prospective study investigates stimulation direction‐dependent and site‐specific effects of theta frequency DBS on VF. Methods In a double‐blind, cross‐
Hannah Schoenwald   +12 more
wiley   +1 more source

Bewertung des Informationspaketes „Wechseljahre“ des IQWiG

open access: yes, 2009
Evidenz und Entscheidung: System unter Druck; 10.
Berger, B   +3 more
openaire   +1 more source

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