Results 1 to 10 of about 58,797 (144)
Enhancing Circular RNA Translation Efficiency Through Dual Internal Ribosome Entry Sites [PDF]
Circular RNA (circRNA) has emerged as a promising vector for drug delivery because, unlike linear mRNA, it does not require costly chemical modifications and offers greater stability and sustained expression in cells.
Yawen Sun +6 more
doaj +2 more sources
Comparison of the Regulatory Effects of Host Factors on Viral Internal Ribosomal Entry Sites [PDF]
Host factors play critical roles in viral IRES-mediated translation by modulating the efficiency and specificity of viral protein synthesis. In this study, we used small interfering RNA (siRNA) treatment to silence and plasmid-based expression to ...
Rupaly Akhter +4 more
doaj +2 more sources
Life cycle assessment of advanced building materials towards NZEBs [PDF]
Buildings are responsible for 40% of energy consumption annually in Europe, along with the respective greenhouse gas emissions. To mitigate these impacts, intensive research is ongoing in the sector of the Nearly Zero-Energy Buildings (NZEBs).
Antypa Despoina +9 more
doaj +1 more source
Background: Eukaryotic initiation factor (eIF) 4G plays an important role in assembling the initiation complex required for ribosome binding to mRNA and promote translation.
Mateen A. Khan
doaj +1 more source
Near-IR & Mid-IR Silicon Photonics Modulators
As the silicon photonics field matures and a data-hungry future looms ahead, new technologies are required to keep up pace with the increase in capacity demand. In this paper, we review current developments in the near-IR and mid-IR group IV photonic modulators that show promising performance.
Georgi V. Georgiev +7 more
openaire +4 more sources
Tanzania is one of the East African countries most vulnerable to climate change impacts. Droughts and floods in 2015–16 had devastating effects on food production, crop failures and livestock deaths reaching record levels.
Idil Ires, Idil Ires
doaj +1 more source
On the Relation Between Active Network Length and Catchment Discharge
The ever‐changing hydroclimatic conditions of the landscape induce ceaseless variations in the wet channel length (L) and the streamflow (Q) of a catchment.
Nicola Durighetto, Gianluca Botter
doaj +1 more source
Extensive research is currently being conducted on nanotechnologies worldwide, and the applications of nanomaterials are continuously expanding.
Ioannis Kokkinopoulos +4 more
doaj +1 more source
A novel Bcr-Abl–mTOR–eIF4A axis regulates IRES-mediated translation of LEF-1 [PDF]
Internal ribosome entry sites (IRESs) in cellular mRNAs direct expression of growth-promoting factors through an alternative translation mechanism that has yet to be fully defined.
Becky Pinjou Tsai +10 more
doaj +1 more source
Pathogenicity and virulence of hepatitis A virus
Hepatitis A is an acute infection of the liver, which is mostly asymptomatic in children and increases the severity with age. Although in most patients the infection resolves completely, in a few of them it may follow a prolonged or relapsed course or ...
Rosa M Pintó +6 more
doaj +1 more source

