Results 11 to 20 of about 58,896 (242)

Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

open access: yesViruses, 2022
Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region.
Jenniffer Angulo   +7 more
doaj   +1 more source

Utilisation of forecasting technology for improving construction logistics in Nigeria

open access: yesActa Structilia, 2020
The need to investigate new technology for forecasting purposes in construction logistics is due to the fact that the forecasting ability (modern technology utilisation) of the Nigerian construction sector, in terms of logistics management, is relatively
Yahaya Isah   +2 more
doaj   +1 more source

Collecting Distributed Knowledge For Community’s Smart Changes

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2013
The paper deals with the role of ICT in innovating government’s and the whole process of “policy production process”. By enhancing the connections between various governmental and social organizations, ICT supported knowledge flow s and the associated ...
Alessandro Sciullo, Sylvie Occelli
doaj   +1 more source

Promotion of Viral IRES-Mediated Translation Initiation under Mild Hypothermia. [PDF]

open access: yesPLoS ONE, 2015
Internal ribosome entry site (IRES)-mediated translation is an essential replication step for certain viruses. As IRES-mediated translation is regulated differently from cap-dependent translation under various cellular conditions, we sought to ...
Maria Licursi   +3 more
doaj   +1 more source

Production and Application of Multicistronic Constructs for Various Human Disease Therapies

open access: yesPharmaceutics, 2019
The development of multicistronic vectors has opened up new opportunities to address the fundamental issues of molecular and cellular biology related to the need for the simultaneous delivery and joint expression of several genes.
Alisa A. Shaimardanova   +7 more
doaj   +1 more source

Viral IRES prediction system - a web server for prediction of the IRES secondary structure in silico. [PDF]

open access: yesPLoS ONE, 2013
The internal ribosomal entry site (IRES) functions as cap-independent translation initiation sites in eukaryotic cells. IRES elements have been applied as useful tools for bi-cistronic expression vectors.
Jun-Jie Hong   +3 more
doaj   +1 more source

Network Screening for Smarter Road Sites: A Regional Case

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2014
Road safety has been a main societal and policy issue in many European countries since the early years of last decade. After the 2000-2010 Road Safety Programme launched by the European Commission, in 2011 the Commission adopted the new 2020 programme ...
Attila Grieco   +3 more
doaj   +1 more source

Science and Management of Intermittent Rivers and Ephemeral Streams (SMIRES) [PDF]

open access: yesResearch Ideas and Outcomes, 2017
More than half of the global river network is composed of intermittent rivers and ephemeral streams (IRES), which are expanding in response to climate change and increasing water demands. After years of obscurity, the science of IRES has bloomed recently
Thibault Datry   +32 more
doaj   +2 more sources

HuR and Ago2 Bind the Internal Ribosome Entry Site of Enterovirus 71 and Promote Virus Translation and Replication. [PDF]

open access: yesPLoS ONE, 2015
EV71 (enterovirus 71) RNA contains an internal ribosomal entry site (IRES) that directs cap-independent initiation of translation. IRES-dependent translation requires the host's translation initiation factors and IRES-associated trans-acting factors ...
Jing-Yi Lin, Gary Brewer, Mei-Ling Li
doaj   +1 more source

The Stem-Loop I of Senecavirus A IRES Is Essential for Cap-Independent Translation Activity and Virus Recovery

open access: yesViruses, 2021
Senecavirus A (SVA) is a picornavirus that causes vesicular disease in swine and the only member of the Senecavirus genus. Like in all members of Picornaviridae, the 5′ untranslated region (5’UTR) of SVA contains an internal ribosome entry site (IRES ...
Nana Wang   +9 more
doaj   +1 more source

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