Results 61 to 70 of about 4,357 (177)

Advanced Glycation End Products: From Pathogenesis to Treatment

MedComm, Volume 7, Issue 10, October 2026.
Therapeutic landscape of AGE‐targeted intervention. Schematic representation of intervention strategies targeting distinct stages of AGE biology. Upstream prevention aims to reduce exposure and formation through low‐AGE cooking, smoking cessation, glycemic control, and metabolic optimization.
Tak‐Ho Lo, Junying Zou, Jingyi Zhang, Kaijun Lin, Minhui Zhu, Shuangqi Lu, Xin Liu, Mengyao Wu   +7 more
wiley   +1 more source

New Glycosides and Trypanocidal Metabolites from

Natural Product Communications, 2015
A new iridoid glucoside, 10-methoxy apodanthoside ( 1 ), and a new monoterpene glycoside, (3S,6S)-cis linalool-3,7-oxide O -β-D-glucopyranosyl-(1′'→5′)-β-D-xylofuranoside ( 2 ), were isolated from V.
Shaymaa M. M. Mohamed, Khaled M. Elokely, Enaam Y. Bachkeet, Soad A. L. Bayoumi, Vincenzo Carnevale, Michael L. Klein, Stephen J. Cutler, Samir A. Ross   +7 more
doaj   +1 more source

New Lignans and Iridoid Glycosides from Dipsacus asper Wall

Molecules, 2015
Six new compounds, including four new lignans, dipsalignan A (1), B–D (3–5), and two new bis-iridoid glycoside dimmers, dipsanosides M (7) and N (8), together with two known compounds (2) and (6), have been isolated from the roots of Dipsacus asper Wall.
Xinguang Sun, Guoxu Ma, Dawei Zhang, Wenhua Huang, Gang Ding, Huagang Hu, Guangzhong Tu, Baolin Guo   +7 more
doaj   +1 more source

Asperuloside Improves Obesity and Type 2 Diabetes through Modulation of Gut Microbiota and Metabolic Signaling

iScience, 2020
Summary: Asperuloside (ASP) is an iridoid glycoside that is extracted from Eucommia leaves. Eucommia is used in traditional Chinese medicine and has a long history of benefits on health and longevity.
Anna Nakamura, Yoko Yokoyama, Kazuki Tanaka, Giorgia Benegiamo, Akiyoshi Hirayama, Qi Zhu, Naho Kitamura, Taichi Sugizaki, Kohkichi Morimoto, Hiroshi Itoh, Shinji Fukuda, Johan Auwerx, Kazuo Tsubota, Mitsuhiro Watanabe   +13 more
doaj   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, Volume 13, Issue 50, 7 September 2026.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Bioassay-Guided Isolation of Anti-Alzheimer Active Components from the Aerial Parts of Hedyotis diffusa and Simultaneous Analysis for Marker Compounds

Molecules, 2020
Previous studies have reported that Hedyotis diffusa Willdenow extract shows various biological activities on cerebropathia, such as neuroprotection and short-term memory enhancement.
Jun Hee Park, Wan Kyunn Whang
doaj   +1 more source

Five New Iridoids From the Leaves of Viburnum macrocephalum f. macrocephalum and Their Free Radical Scavenging Activity

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Five new iridoids, viburetins D–H, featuring dioxatricyclodecane and ring‑opened monocyclic skeletons, are isolated from the leaves of Viburnum macrocephalum f. macrocephalum, enriching the chemical diversity of Viburnum. Preliminary DPPH and ABTS assays reveal varying degrees of radical scavenging activity.
Ya‐Jiao Chen, Hong‐Juan Zhou, Jia Chen, Jian‐Hua Shao, Chun‐Chao Zhao   +4 more
wiley   +1 more source

Pharmacokinetics and Tissue Distribution in Rats After Oral Administration of Tibetan Medicine Wuwei Leze Powder

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Wuwei Leze Powder (WLP), a classic Tibetan medicine for rheumatoid arthritis, is orally administered and undergoes extensive absorption and metabolism in rats. A total of 56 plasma constituents, including 21 prototypes and 35 metabolites, are identified.
Ping Wang, Peng Wang, YiRui Wu, ShuiYing Wu, HuiJuan Xu, WenYu Yang, Ya Tu, Chuan Liu   +7 more
wiley   +1 more source

HỢP CHẤT IRIDOID GLYCOSIDE TỪ LOÀI Gomphandra tonkinensis Gagnep.

Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên
Bốn hợp chất iridoid glycoside bao gồm sweroside (1), loganin (2), triplostoside A (3) và gomphandranoside C (4) được phân lập từ rễ loài Gomphandra tonkinensis Gagnep. thu hái tại Thừa Thiên Huế.
Tran Phan Thi Diem, Ha Tran Phuong, Tam Vu Thi Thanh, Dat Ton That Huu, Hieu Le Trung, Le Canh Viet Cuong   +5 more
doaj   +1 more source

Biological Activities and Analytical Methods for Detecting Aucubin and Catalpol Iridoid Glycosides in Plantago Species: A Review Study [PDF]

Pharmaceutical and Biomedical Research, 2023
Background: Plantago species contain aucubin and catalpol iridoid glycosides used in traditional medicine for many purposes. Objectives: To accelerate the utilization of aucubin and catalpol in Plantago species, research should be focused on introducing ...
Samaneh Rahamouz-Haghighi
doaj