Results 51 to 60 of about 4,357 (177)

Chemical Constituents of the Whole Plant of and Their Inhibitory Activity Against the Production of AGEs

Natural Product Communications, 2021
Two iridoid glycosides ( 1 and 2 ), 3 phenolic glycosides ( 3–5 ), 1 flavone glycoside ( 6 ), 3 biflavonoids ( 7–9 ), 1 flavone ( 10 ), 2 triterpenes ( 11 and 12 ), 1 sterol ( 13 ), and 1 naphthoquinone derivative ( 14 ) were isolated from the whole ...
Akihito Yokosuka, Misaki Honda, Hitoshi Kondo, Yoshihiro Mimaki   +3 more
doaj   +1 more source

Fermented Noni Juice Supplementation Attenuates Heart Failure Development in Mice: Involvement of the Pentose Phosphate Pathway

Food Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Morinda citrifolia L., commonly known as Noni, is a traditional medicinal plant that has long been utilized in various cultures for its anti‐inflammatory and antioxidant properties. Heart failure (HF) is a significant and growing public health concern worldwide that is characterized by substantial morbidity, mortality, and healthcare costs ...
Min Zhang, Xia Guan, Ruize Lu, Zhangxin Yu, Xuanjia Chen, Jingyao Xu, Guangying Chen, Haiying Zhang, Yan Liu   +8 more
wiley   +1 more source

Preference, performance, and chemical defense in an endangered butterfly using novel and ancestral host plants

Scientific Reports, 2021
Adoption of novel host plants by herbivorous insects can require new adaptations and may entail loss of adaptation to ancestral hosts. We examined relationships between an endangered subspecies of the butterfly Euphydryas editha (Taylor’s checkerspot ...
Nathan L. Haan, M. Deane Bowers, Jonathan D. Bakker   +2 more
doaj   +1 more source

Synergistic Phytochemicals From Mitracarpus frigidus (Willd. ex Roem. & Schult.) K. Schum. and Lantana camara Linn. in Chitosan Biofilms: Antioxidant and Anti‐Inflammatory Activities With Wound‐Healing Potential

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Biodegradable chitosan films loaded with a 1:1 combination of Mitracarpus frigidus and Lantana camara extracts demonstrated potent antioxidant, anti‐inflammatory, and wound‐healing properties, while exhibiting low cytotoxicity and favorable physicochemical characteristics.
Natasha Silva Mayrink, Julia Bertolini Fajardo, Mariane Rocha Cordeiro Comitre, Lucas de Araújo Carvalho, Mariana Iasbeck Dalcol, Priscila de Lima Paula, Lara Melo Campos, Maria Clara Machado Resende Guedes, Luiz Fernando Cappa de Oliveira, Elaine Soares Coimbra, Gilson Costa Macedo, Ângelo Márcio Leite Denadai, Ari Sérgio de Oliveira Lemos, Rodrigo Luiz Fabri   +13 more
wiley   +1 more source

Exploring the Neuropharmacological Potential of Ligustrum sinense Relevant to Parkinson's Disease: In Vivo and In Silico Study

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ligustrum sinense (L. sinense) leaf extract exhibited moderate antioxidant activity (DPPH IC50 = 73.56 ± 2.18 µg/mL) and was evaluated for neuropharmacological effects at 200 and 400 mg/kg using elevated plus maze, open‐field, hole‐cross, and hole‐board tests.
Sowmitro Das, S. M. Istiaque Hamim, Md Nazmul Hasan Zilani, Kazi Sneha Chhando, Puza Das, Md Ridoy Hossain, Md. Imtiaz, Jebin Tasmin, Roney Miah, Md. Nazmul Hasan   +9 more
wiley   +1 more source

In Vivo Hepatoprotective and Nephroprotective Activity of Acylated Iridoid Glycosides from Scrophularia hepericifolia

Biology, 2021
Phytochemical investigation of the chloroform fraction obtained from Scrophularia hypericifolia aerial parts led to the isolation of nine acylated iridoid glycosides.
Maged S. Abdel-Kader, Saleh I. Alqasoumi
doaj   +1 more source

UPLC‐Q‐TOF‐MS/MS Profiling and Synergistic Anti‐HCC Activity of Gallic Acid From Compound Muji Granules Combined With hUC‐MSC‐Exos

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang, Yige Wang, Jinnan Huo, Liying Han, Ying Meng, Yuanyuan Li, Jiaxin Shi, Xi Wu, Yongrui Bao, Shuai Wang, Tianjiao Li, Jiapeng Leng, Xiansheng Meng   +12 more
wiley   +1 more source

Phytochemical Investigation of Stachys hissarica: Antioxidant Activity, Flavonoid Characterization, and In Silico Analysis

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Stachys hissarica demonstrates remarkable antioxidant potential, driven by a rich profile of 35 annotated polyphenolic metabolites within its aqueous methanolic extract. Hydrophilic phenolics exhibit superior radical‐scavenging activity comparable to ascorbic acid. Integrated computational simulations reveal favorable oral bioavailability, low toxicity,
Elbek A. Mukhammadiev, Michal Šoral, Francesco Cacciola, Katia Arena, Chao Liu, Mengqi Zhang, Ruirui Zhang, Doniyor R. Siddikov, Sobirdjan A. Sasmakov, Nilufar Z. Mamadalieva   +9 more
wiley   +1 more source

Host Plant Effects on Immune Response Across Development of a Specialist Caterpillar

Frontiers in Ecology and Evolution, 2019
Some herbivorous insects sequester chemicals from their host plants, which can serve as a defense against predators. However, sequestration can also be costly, impacting immunological responses important for other types of natural enemies, such as ...
Adrian L. Carper, Micaela Enger, M. Deane Bowers   +2 more
doaj   +1 more source

Aucubin Alleviates Ulcerative Colitis in Mice by Repairing the Intestinal Barrier and Modulating the Microbiota‐Metabolism Axis

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Aucubin (Auc), an iridoid glycoside, alleviates dextran sulfate sodium (DSS)‐induced ulcerative colitis (UC) in mice through a microbiota–metabolite–barrier axis. Preventive Auc (100 mg/kg) attenuates body‐weight loss, Disease Activity Index elevation and colon shortening to an extent comparable to 5‐aminosalicylic acid. It reshapes the gut microbiota (
Yanghui Bi, Pengyu Chen, Shuya Jia, Shiyan Jia, Zhanhao Lian, Yuanfang Zheng, Jiabin Guo, Jianxia Xue, Sinan Cheng   +8 more
wiley   +1 more source