Results 11 to 20 of about 4,023 (177)

Iridoid Sex Pheromone Biosynthesis in Aphids Mimics Iridoid‐Producing Plants [PDF]

Chemistry – A European Journal, 2021
AbstractBiosynthesis of (1R,4aS,7S,7aR)‐nepetalactol (1) and (4aS,7S,7aR)‐nepetalactone (2) in plants involves iridoid synthase (ISY), an atypical reductive cyclase that catalyses the reduction of 8‐oxogeranial into the reactive enol of (S)‐8‐oxocitronellal, and cyclization of this enol intermediate, either non‐enzymatically or by a nepetalactol ...
Suzanne J. Partridge, David M. Withall, John C. Caulfield, John A. Pickett, Robert A. Stockman, Neil J. Oldham, Michael A. Birkett   +6 more
openaire   +2 more sources

Nine Unique Iridoids and Iridoid Glycosides From Patrinia scabiosaefolia [PDF]

Frontiers in Chemistry, 2021
Patrinia scabiosaefolia is a medical and edible Chinese herb with high nutritional and medicinal value. The continuing study of its chemical constituents led to the discovery of nine unique iridoids and iridoid glycosides, including three new iridoids (1-3) and six previously unknown irioid glycosides (5-10), and one known compound (4).
Zhenhua Liu, Zhenhua Liu, Zhenhua Liu, Yun Niu, Yun Niu, Li Zhou, Li Zhou, Lijun Meng, Lijun Meng, Sitan Chen, Sitan Chen, Mengke Wang, Mengke Wang, Jiangmiao Hu, Jiangmiao Hu, Wenyi Kang, Wenyi Kang   +16 more
openaire   +3 more sources

Discovery of iridoid cyclase completes the iridoid pathway in asterids. [PDF]

Nat Plants
Abstract Iridoids are specialized monoterpenes ancestral to asterid flowering plants 1,2 that play key roles in defence and are also essential precursors for pharmacologically important alkaloids 3,4 .
Colinas M, Tymen C, Wood JC, David A, Wurlitzer J, Morweiser C, Gase K, Alam RM, Titchiner GR, Hamilton JP, Heinicke S, Dirks RP, Lopes AA, Caputi L, Buell CR, O'Connor SE.   +15 more
europepmc   +5 more sources

Antimicrobial and Immunomodulating Activities of Two Endemic Nepeta Species and Their Major Iridoids Isolated from Natural Sources

Pharmaceuticals, 2021
Two Balkan Peninsula endemics, Nepeta rtanjensis and N. argolica subsp. argolica, both characterized by specialized metabolite profiles predominated by iridoids and phenolics, are differentiated according to the stereochemistry of major iridoid aglycone ...
Neda Aničić, Uroš Gašić, Feng Lu, Ana Ćirić, Marija Ivanov, Bojan Jevtić, Milena Dimitrijević, Boban Anđelković, Marijana Skorić, Jasmina Nestorović Živković, Yingle Mao, Jia Liu, Chunping Tang, Marina Soković, Yang Ye, Danijela Mišić   +15 more
doaj   +1 more source

Iridoids from Stachys byzantina K. Koch (Lamb's Ears) and Stachys germanica L. (Downy Woundwort)

European Pharmaceutical Journal, 2021
Iridoids are a class of secondary metabolites found in a wide variety of plants. Iridoids are typically found in plants as glycosides, most often found to glucose. The genus Stachys L.
Háznagy-Radnai E., Czigle Sz., Máthé I.   +2 more
doaj   +1 more source

Iridoids, Flavonoids, and Antioxidant Capacity of Cornus mas, C. officinalis, and C. mas × C. officinalis Fruits

Biomolecules, 2021
The fruits of Cornus mas and Cornus officinalis have been known and appreciated in folk medicine for years and have a high biological value, which is mainly connected with their polyphenols and iridoids content. However, hybrids of C.
Svitlana Klymenko, Alicja Zofia Kucharska, Anna Sokół-Łętowska, Narcyz Piórecki, Dominika Przybylska, Olga Grygorieva   +5 more
doaj   +1 more source

Iridoids and bis-iridoids from Patrinia scabiosaefolia

RSC Advances, 2017
Ten new iridoids, patriscabioins A–J (1–10), and three unique bis-iridoids, patriscabiobisins A–C (11–13), together with seven known analogues, have been identified from whole plants of Patrinia scabiosaefolia.
Zhen-Hua Liu, Bo Hou, Liu Yang, Rui-Jing Ma, Jin-Yu Li, Jiang-Miao Hu, Jun Zhou   +6 more
openaire   +4 more sources

Iridoids from Globularia dumulosa [PDF]

Zeitschrift für Naturforschung C, 2003
Two new iridoids, 10-O-benzoylglobularigenin (1) and dumuloside (2) were isolated from the aerial parts of Globularia dumulosa together with seven known iridoid glucosides, davisioside (3), aucubin (4), melampyroside (5), catalpol (6), 10-O-benzoylcatalpol (7), alpinoside (8) and deacetylalpinoside (9).
Kirmizibekmez, H, Akbay, P, Sticher, O, Çaliş, I.   +3 more
openaire   +4 more sources

Establishing the Role of Iridoids as Potential Kirsten Rat Sarcoma Viral Oncogene Homolog G12C Inhibitors Using Molecular Docking; Molecular Docking Simulation; Molecular Mechanics Poisson–Boltzmann Surface Area; Frontier Molecular Orbital Theory; Molecular Electrostatic Potential; and Absorption, Distribution, Metabolism, Excretion, and Toxicity Analysis

Molecules, 2023
The RAS gene family is one of the most frequently mutated oncogenes in human cancers. In KRAS, mutations of G12D and G12C are common. Here, 52 iridoids were selected and docked against 8AFB (KRAS G12C receptor) using Sotorasib as the standard. As per the
Mubarak A. Alamri, Abdullah S. Alawam, Mohammed Merae Alshahrani, Sarkar M. A. Kawsar, Prinsa, Supriyo Saha   +5 more
doaj   +1 more source

Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome

Cellular Physiology and Biochemistry, 2017
Background/Aims: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women, and it is usually characterized by chronic inflammation, oxidative stress, and altered microRNA expression. The aim of this study is to investigate how the effects
Tao Zuo, Minghui Zhu, Wenming Xu, Zhixia Wang, Hang Song   +4 more
doaj   +1 more source