Results 61 to 70 of about 6,410 (167)

Integrated Metabolomics and Selection Signal Analysis Provide Insights Into the Selection for Flavonol Biosynthesis Associated With Lettuce Quality Improvement

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Lettuce is a critical leafy vegetable consumed worldwide and is a substantial dietary source of health‐promoting compounds. Exploring changes in metabolism during lettuce domestication under artificial selection conditions is important to facilitate further breeding and cultivation for quality improvement.
Xiao Yang   +17 more
wiley   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

open access: yesAngewandte Chemie, Volume 138, Issue 36, 1 September 2026.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu   +6 more
wiley   +2 more sources

Iridoids and polyphenols found in young sesame leaves.

open access: yes, 2018
Iridoids and polyphenols found in young sesame leaves.
Yushiro Fuji (5018672)   +5 more
core   +1 more source

A study of a complex of bioactive compounds in the fruits of promising blue honeysuckle (Lonicera caerulea L.) cultivars

open access: yesТруды по прикладной ботанике, генетике и селекции, 2023
Background. Blue honeysuckle (Lonicera caerulea L.) is a valuable source of bioactive compounds (BAC) of polyphenolic nature and rare for horticultural berries iridoids, which have antioxidant, anti-inflammatory, antimicrobial and other properties and ...
I. B. Perova   +7 more
doaj   +1 more source

Fermented Noni Juice Supplementation Attenuates Heart Failure Development in Mice: Involvement of the Pentose Phosphate Pathway

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Morinda citrifolia L., commonly known as Noni, is a traditional medicinal plant that has long been utilized in various cultures for its anti‐inflammatory and antioxidant properties. Heart failure (HF) is a significant and growing public health concern worldwide that is characterized by substantial morbidity, mortality, and healthcare costs ...
Min Zhang   +8 more
wiley   +1 more source

Synergistic Phytochemicals From Mitracarpus frigidus (Willd. ex Roem. & Schult.) K. Schum. and Lantana camara Linn. in Chitosan Biofilms: Antioxidant and Anti‐Inflammatory Activities With Wound‐Healing Potential

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Biodegradable chitosan films loaded with a 1:1 combination of Mitracarpus frigidus and Lantana camara extracts demonstrated potent antioxidant, anti‐inflammatory, and wound‐healing properties, while exhibiting low cytotoxicity and favorable physicochemical characteristics.
Natasha Silva Mayrink   +13 more
wiley   +1 more source

Exploring the Neuropharmacological Potential of Ligustrum sinense Relevant to Parkinson's Disease: In Vivo and In Silico Study

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ligustrum sinense (L. sinense) leaf extract exhibited moderate antioxidant activity (DPPH IC50 = 73.56 ± 2.18 µg/mL) and was evaluated for neuropharmacological effects at 200 and 400 mg/kg using elevated plus maze, open‐field, hole‐cross, and hole‐board tests.
Sowmitro Das   +9 more
wiley   +1 more source

UPLC‐Q‐TOF‐MS/MS Profiling and Synergistic Anti‐HCC Activity of Gallic Acid From Compound Muji Granules Combined With hUC‐MSC‐Exos

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang   +12 more
wiley   +1 more source

Iridoids as DNA topoisomerase I poisons [PDF]

open access: yes, 2005
The discovery of new topoisomerase I inhibitors is necessary since most of the antitumor drugs are targeted against type II and only a very few can specifically affect type I.
Gálvez, Marina   +2 more
core   +1 more source

Phytochemical Characterization and Biological Activity of Stachys pinardii Extracts

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Ultrasound‐assisted methanol and aqueous extracts of Stachys pinardii are comparatively evaluated for phytochemical composition and biological activities. Solvent polarity markedly influences phenolic profiles and bioactivity. Although the methanolic extract contains higher total phenolics, the aqueous extract exhibits superior antioxidant and enzyme ...
Zeyneb Karakus   +2 more
wiley   +1 more source

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