Results 61 to 70 of about 6,410 (167)
ABSTRACT Lettuce is a critical leafy vegetable consumed worldwide and is a substantial dietary source of health‐promoting compounds. Exploring changes in metabolism during lettuce domestication under artificial selection conditions is important to facilitate further breeding and cultivation for quality improvement.
Xiao Yang +17 more
wiley +1 more source
Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu +6 more
wiley +2 more sources
Iridoids and polyphenols found in young sesame leaves.
Iridoids and polyphenols found in young sesame leaves.
Yushiro Fuji (5018672) +5 more
core +1 more source
Background. Blue honeysuckle (Lonicera caerulea L.) is a valuable source of bioactive compounds (BAC) of polyphenolic nature and rare for horticultural berries iridoids, which have antioxidant, anti-inflammatory, antimicrobial and other properties and ...
I. B. Perova +7 more
doaj +1 more source
ABSTRACT Morinda citrifolia L., commonly known as Noni, is a traditional medicinal plant that has long been utilized in various cultures for its anti‐inflammatory and antioxidant properties. Heart failure (HF) is a significant and growing public health concern worldwide that is characterized by substantial morbidity, mortality, and healthcare costs ...
Min Zhang +8 more
wiley +1 more source
Biodegradable chitosan films loaded with a 1:1 combination of Mitracarpus frigidus and Lantana camara extracts demonstrated potent antioxidant, anti‐inflammatory, and wound‐healing properties, while exhibiting low cytotoxicity and favorable physicochemical characteristics.
Natasha Silva Mayrink +13 more
wiley +1 more source
Ligustrum sinense (L. sinense) leaf extract exhibited moderate antioxidant activity (DPPH IC50 = 73.56 ± 2.18 µg/mL) and was evaluated for neuropharmacological effects at 200 and 400 mg/kg using elevated plus maze, open‐field, hole‐cross, and hole‐board tests.
Sowmitro Das +9 more
wiley +1 more source
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang +12 more
wiley +1 more source
Iridoids as DNA topoisomerase I poisons [PDF]
The discovery of new topoisomerase I inhibitors is necessary since most of the antitumor drugs are targeted against type II and only a very few can specifically affect type I.
Gálvez, Marina +2 more
core +1 more source
Phytochemical Characterization and Biological Activity of Stachys pinardii Extracts
Ultrasound‐assisted methanol and aqueous extracts of Stachys pinardii are comparatively evaluated for phytochemical composition and biological activities. Solvent polarity markedly influences phenolic profiles and bioactivity. Although the methanolic extract contains higher total phenolics, the aqueous extract exhibits superior antioxidant and enzyme ...
Zeyneb Karakus +2 more
wiley +1 more source

