Results 171 to 180 of about 79,311 (270)

Metabolomic Study of 7-Ethyl-9-(<i>N</i>-methyl)aminomethyl-10-hydroxycamptothecin Derivative (NMe)-The Chemotherapeutic Drug Candidate Versus Irinotecan (IR) on a Mouse Model. [PDF]

Metabolites
Surynt P, Naumczuk B, Popławska M, Urbanowicz M, Unrug-Bielawska K, Cybulska-Lubak M, Sadowska-Markiewicz Z, Sitkowski J, Bednarek E, Zeber-Lubecka N, Kozerski L, Mikula M, Ostrowski J.   +12 more
europepmc   +1 more source

Efficacy of the combined use of bevacizumab and irinotecan in a human colorectal cancer xenograft model analysed by SPECT imaging [PDF]

, 2011
Geboes, Karen, Laurent, Stéphanie, Peeters, Marc, Van Damme, Nancy, Van De Wiele, Christophe, VANGESTEL, CHRISTEL   +5 more
core   +1 more source

Isoquercitrin Alleviates 5‐Fluorouracil‐Induced Intestinal Mucositis in Mice by Modulating Inflammation and Oxidative Stress

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT This study aimed to evaluate the role of isoquercitrin (ISO) in 5‐fluorouracil‐induced intestinal mucositis. The animals (6 animals/group) were divided into: vehicle (2% DMSO), 5‐fluorouracil (5‐FU) and groups receiving ISO (10, 50, or 100 mg/kg).
Lázaro de Sousa Fideles, Matheus da Silva Campelo, João Francisco Câmara Neto, Conceição da Silva Martins, João Erivan Façanha Barreto, Ícaro Gusmão Pinto Vieira, Nágila Maria Pontes Silva Ricardo, Gilberto Santos Cerqueira, Maria Elenir Nobre Pinho Ribeiro   +8 more
wiley   +1 more source

Evaluation of the efficacy and tolerability of bevacizumab-based treatments in recurrent primary brain tumors: a multicenter real-world Turkish Oncology Group (TOG) study. [PDF]

BMC Cancer
Sucuoğlu İşleyen Z, Seçmeler Ş, Sakin A, Cihan Ş, Beşiroğlu M, Kahraman S, Karakurt Eryılmaz M, Zeynelgil E, Çalışkan Yıldırım E, Kut E, Şengül N, Paksoy Türköz F, Alan Ö, Özkul Ö, Işık S, Yılmaz F, Gülmez A, Türker S, Karakaya G, Günaldı M, Özer L, Aksoy A, Karataş F, Sakalar T, Demirtaş Esmer D, Teker F, Demir N, Dülgar Ö, Turhal S, Türk HM, Ertürk K, Çelik E, Atcı MM.   +32 more
europepmc   +1 more source

Clinical Evidence for Three Distinct Gastric Cancer Subtypes: Time for a New Approach [PDF]

, 2013
Bearzi Italo, Bianconi Maristella, Bittoni Alessandro, Cascinu Stefano, Cecchini Luca, Del Prete Michela, Faloppi Luca, Giampieri Riccardo, Mandolesi Alessandra, Pistelli Mirco, SCARTOZZI, MARIO   +10 more
core   +1 more source

Pre‐Emptive Amlodipine for FOLFIRINOX‐Induced Hypertensive Crises Without Primary Hypertension: A Novel Chronotherapeutic Strategy

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT FOLFIRINOX remains a cornerstone therapy for advanced pancreatic ductal adenocarcinoma (PDAC), but its toxicity profile extends beyond myelosuppression and neuropathy to include even rarer complications such as treatment‐associated hypertension.
Manas Pustake, William Wells‐Gatnik, Vani Shukla, Javier Corral, Sumit Gaur   +4 more
wiley   +1 more source

FASN Inhibition Enhances the Efficacy of Chemotherapy in Colorectal Cancer by Inhibiting the DNA Damage Response. [PDF]

Cancer Res
Banerjee M, Zaytseva YY, Reusch EM, Napier DL, Hasani S, Rychahou P, Izumi T, Cheek DA, Li J, Flight RM, Moseley HNB, Weiss HL, McCulloch W, Evers BM, Gao T.   +14 more
europepmc   +1 more source

External Auditory Canal Metastasis of Colorectal Adenocarcinoma: A Comprehensive Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Metastatic colorectal adenocarcinoma with a single‐site metastasis to the external auditory canal is an exceedingly rare phenomenon. A multidisciplinary approach involving collaboration among various medical specialties is essential for optimizing patient care and improving survival outcomes.
Luna Sissa, Stefano Cardelli, Deborah Malvi, Gilberto Poggioli, Matteo Rottoli, Giacomo Calini   +5 more
wiley   +1 more source

Bevacizumab-Based Therapy Is Associated with Prolonged Progression-Free Survival in Patients with Peritoneal Mucinous Metastatic Colorectal Cancer. [PDF]

J Clin Med
Can S, Çakıcı V, Kahveci GB, Eroğlu Ş, Tok B, Uygun G, Özer E, Çırak Y, Gökmen İ.   +8 more
europepmc   +1 more source

Novel insights into extracellular vesicles: An update on biomolecules, immunomodulation and clinical strategies in skin melanoma

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Extracellular vesicles mediate melanoma progression by transferring biomolecules (proteins, nucleic acids) that reshape the tumour microenvironment, promote immune evasion and drive metastasis. They also serve as diagnostic biomarkers and engineered therapeutic carriers for targeted therapy.
Junshu Li, Wencheng Zhou, Ying Cen, Yong Qing   +3 more
wiley   +1 more source