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Endocrine, 2017
Irisin is a myokine/adipokine induced by the exercise in mice and humans, which is proposed to induce "browning" of white adipose tissue, its primary target, thus increasing thermogenesis and energy expenditure. Since its identification, irisin has been linked to favorable effects on metabolic diseases, including obesity, type 2 diabetes mellitus (T2DM)
Polyzois Makras +6 more
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Irisin is a myokine/adipokine induced by the exercise in mice and humans, which is proposed to induce "browning" of white adipose tissue, its primary target, thus increasing thermogenesis and energy expenditure. Since its identification, irisin has been linked to favorable effects on metabolic diseases, including obesity, type 2 diabetes mellitus (T2DM)
Polyzois Makras +6 more
openaire +2 more sources
Acta Physiologica
To reveal the contribution of Irisin in the beneficial effects of resistance exercise on myocardial fibrosis (MF) and cardiac function in the mice with myocardial infarction (MI).
Hangzhuo Li +13 more
semanticscholar +1 more source
To reveal the contribution of Irisin in the beneficial effects of resistance exercise on myocardial fibrosis (MF) and cardiac function in the mice with myocardial infarction (MI).
Hangzhuo Li +13 more
semanticscholar +1 more source
The role of Irisin in multiorgan protection
Molecular Biology Reports, 2021Physical exercise is an effective strategy for improving human health. Various organs, including the heart, lung and kidney, can benefit from exercise. However, the underlying molecular mechanisms by which exercise protects organs remain unknown. Irisin, a myokine secreted from muscle in response to exercise, has attracted increased attention from ...
Jun Ma, Ken Chen
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Advancement of science
Acute kidney injury (AKI) is the sudden decrease in renal function that can be attributed to dysregulated reactive oxygen species (ROS) production and impaired mitochondrial function.
Xia Zhang +5 more
semanticscholar +1 more source
Acute kidney injury (AKI) is the sudden decrease in renal function that can be attributed to dysregulated reactive oxygen species (ROS) production and impaired mitochondrial function.
Xia Zhang +5 more
semanticscholar +1 more source
Is irisin a human exercise gene? [PDF]
Nature, 2012 Arising from P. Bostrom , 463–468 (2012)10.1038/nature10777 Bostrom et al. report that exercise training induces the expression of the FNDC5 gene in human muscle, producing irisin, which can convert white fat into brown fat, so enhancing metabolic uncoupling and hence ...
James A. Timmons +3 more
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European Heart Journal, 2022
AIMS Exercise confers protection against cardiovascular ageing, but the mechanisms remain largely unknown. This study sought to investigate the role of fibronectin type-III domain-containing protein 5 (FNDC5)/irisin, an exercise-associated hormone, in ...
C. Chi +18 more
semanticscholar +1 more source
AIMS Exercise confers protection against cardiovascular ageing, but the mechanisms remain largely unknown. This study sought to investigate the role of fibronectin type-III domain-containing protein 5 (FNDC5)/irisin, an exercise-associated hormone, in ...
C. Chi +18 more
semanticscholar +1 more source
New England Journal of Medicine, 2019
Irisin — Gnawing Bone and Heating Fat A recent study suggests that irisin, a cytokine secreted by muscle during exercise, effects bone resorption and the differentiation of preadipocytes into therm...
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Irisin — Gnawing Bone and Heating Fat A recent study suggests that irisin, a cytokine secreted by muscle during exercise, effects bone resorption and the differentiation of preadipocytes into therm...
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2016
Irisin is one of the most recently discovered and isolated hormones, derived from mouse skeletal muscle in 2012. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin consists of 112 aa residues.
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Irisin is one of the most recently discovered and isolated hormones, derived from mouse skeletal muscle in 2012. Irisin is secreted from muscles in response to exercise and may mediate some beneficial effects of exercise in humans, such as weight loss and thermoregulation. Irisin consists of 112 aa residues.
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Clinica Chimica Acta
Irisin, a hormone-like adipo-myokine, has garnered considerable attention in recent years for its potential impact in metabolic diseases. Its physiological effects are similar to those of thyroid hormones, prompting numerous investigations into potential correlations and interactions between irisin and thyroid function through various in vitro and ...
Qi, Chen +5 more
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Irisin, a hormone-like adipo-myokine, has garnered considerable attention in recent years for its potential impact in metabolic diseases. Its physiological effects are similar to those of thyroid hormones, prompting numerous investigations into potential correlations and interactions between irisin and thyroid function through various in vitro and ...
Qi, Chen +5 more
openaire +2 more sources
Irisin in Coronary Bypass Surgery
Cardiovascular & Hematological Disorders-Drug Targets, 2018In coronary bypass surgery, after cardiopulmonary bypass is initiated by arterial cannulation in the ascending aorta and venous cannulation through a single vein generally in the right atrium, the process of cooling the patient is started.There is a relation between cooling the patient and irisin, which is responsible for releasing heat. Therefore, the
Suleyman Aydin +4 more
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