Results 81 to 90 of about 19,243 (300)
Irisin: A myokine with locomotor activity [PDF]
Neuroscience Letters, 2015 The mechanisms underlying alterations in brain functions in response to physical exercise are not fully understood. The present study examined the central effect of irisin, a 112 amino acid polypeptide hormone secreted from the skeletal muscle after exercise, on the locomotion in rats.
Chao Zhang +9 more
openaire +3 more sources
Irisin and the Metabolic Phenotype of Adults with Prader-Willi Syndrome. [PDF]
PLoS ONE, 2015 Hyperphagia, low resting energy expenditure, and abnormal body composition contribute to severe obesity in Prader Willi syndrome (PWS). Irisin, a circulating myokine, stimulates "browning" of white adipose tissue resulting in increased energy expenditure
Harry J Hirsch +4 more
doaj +1 more source
Impact of Exercise Intensity on Cerebral BDNF Levels: Role of FNDC5/Irisin
International Journal of Molecular SciencesThe positive effects of physical exercise (EX) are well known to be mediated by cerebral BDNF (brain-derived neurotrophic factor), a neurotrophin involved in learning and memory, the expression of which could be induced by circulating irisin, a peptide ...
Clémence Leger +8 more
semanticscholar +1 more source
Circulating Irisin Is Reduced in Male Patients with Type 1 and Type 2 Myotonic Dystrophies
Frontiers in Endocrinology, 2017 ContextMyotonic dystrophies (DM) are dominantly inherited muscle disorders characterized by myotonia, muscle weakness, and wasting. The reasons for sarcopenia in DMs are uncleared and multiple factors are involved. Irisin, a positive hormone regulator of
Elena Dozio +13 more
doaj +1 more source
Scientific ReportsThis study aimed to investigate the effects of exercise on excessive mitochondrial fission, insulin resistance, and inflammation in the muscles of diabetic rats.
Junjie Lin +10 more
semanticscholar +1 more source
Time-dependent unloading effects on muscle and bone and involvement of FNDC5/irisin axis
npj Microgravity, 2023 The identification of biomarkers and countermeasures to prevent the adverse effects on the musculoskeletal system caused by the absence of mechanical loading is the main goal of space biomedical research studies.
L. Sanesi +10 more
semanticscholar +1 more source
Is Irisin Anticancer Agent? [PDF]
The 2nd International Cell Death Research Congress, 2018 Irisin is a protein, which is encoded by the FNDC5 gene. Irisin secreted as a hormone secret via Fibronectin type III domain-containing protein 5. Irisin is always provide beneficial effect of exercise on cellular metabolism as well as obesity and metabolic diseases. In addition, it plays a role in cancer.
openaire +3 more sources
Endocrinology, Diabetes & Metabolism, 2023 Insulin resistance and obesity have been associated with irisin, a protein in fat cells. The levels of irisin in patients with type 2 diabetes mellitus (T2DM) were significantly lower than those in non‐diabetics.
T. Ahmed +7 more
semanticscholar +1 more source
Role of irisin in Chinese patients with hypothyroidism: an interventional study
Journal of International Medical Research, 2019 Objective Irisin is a myokine that greatly affects energy expenditure and systemic metabolism. While thyroid hormone is likely associated with irisin, a direct relationship remains to be fully elucidated.
Ning Yang +6 more
doaj +1 more source
International Journal on Biological SciencesVascular remodeling plays a vital role in hypertensive diseases and is an important target for hypertension treatment. Irisin, a newly discovered myokine and adipokine, has been found to have beneficial effects on various cardiovascular diseases. However,
Ruli Li +21 more
semanticscholar +1 more source