Iron-induced changes in the proteome of Trichomonas vaginalis hydrogenosomes. [PDF]
PLoS ONE, 2013 Iron plays a crucial role in metabolism as a key component of catalytic and redox cofactors, such as heme or iron-sulfur clusters in enzymes and electron-transporting or regulatory proteins.
Neritza Campo Beltrán +7 more
doaj +1 more source
Differentiated, promoter-specific response of [4Fe-4S] NsrR DNA-binding to reaction with nitric oxide [PDF]
, 2016 NsrR is an iron-sulfur cluster protein that regulates the nitric oxide (NO) stress response of many bacteria. NsrR from Streptomyces coelicolor regulates its own expression and that of only two other genes, hmpA1 and hmpA2, which encode HmpA enzymes ...
Crack, Jason +5 more
core +1 more source
Influence of association state and DNA binding on the O2-reactivity of [4Fe-4S] fumarate and nitrate reduction (FNR) regulator [PDF]
, 2014 The fumarate and nitrate reduction (FNR) regulator is the master switch for the transition between anaerobic and aerobic respiration in Escherichia coli.
Andrew J. Thomson +41 more
core +1 more source
Frontiers in Molecular Biosciences, 2018 IscX (or YfhJ) is a protein of unknown function which takes part in the iron-sulfur cluster assembly machinery, a highly specialized and essential metabolic pathway. IscX binds to iron with low affinity and interacts with IscS, the desulfurase central to
Salvatore Adinolfi +12 more
doaj +1 more source
Escherichia coli RIC is able to donate iron to iron-sulfur clusters. [PDF]
PLoS ONE, 2014 Escherichia coli RIC (Repair of Iron Centers) is a diiron protein previously reported to be involved in the repair of iron-sulfur proteins damaged by oxidative or nitrosative stresses, and proposed to act as an iron donor.
Lígia S Nobre +6 more
doaj +1 more source
TtcA a new tRNA-thioltransferase with an Fe-S cluster [PDF]
, 2014 International audienceTtcA catalyzes the post-transcriptional thiolation of cytosine 32 in some tRNAs. The enzyme from Es-cherichia coli was homologously overexpressed in E. coli.
Atta, Mohamed +6 more
core +4 more sources
Hybrid Methods in Iron-Sulfur Cluster Biogenesis [PDF]
Frontiers in Molecular Biosciences, 2017 Hybrid methods, which combine and integrate several biochemical and biophysical techniques, have rapidly caught up in the last twenty years to provide a way to obtain a fuller description of proteins and molecular complexes with sizes and complexity otherwise not easily affordable.
Prischi, Filippo, Pastore, Annalisa
openaire +4 more sources
Probing the coordination and function of Fe4S4 modules in nitrogenase assembly protein NifB
Nature Communications, 2018 NifB is a key enzyme in the biosynthesis pathway of the nitrogenase FeMo cofactor. Here, the authors investigate the maturation of its iron-sulfur clusters by EPR and biochemical analyses, showing how individual precursor clusters participate in the ...
Lee A. Rettberg +6 more
doaj +1 more source
Opposite Regulatory Effects of Iron Ions on the In Vitro Catalytic Activities of NarE, the Toxin-like ADP-ribosyltransferase from Neisseria meningitidis [PDF]
, 2015 NarE, the mono ADP-ribosyltransferase identified in Neisseria meningitidis, catalyzes three enzymatic reactions. NarE transfers a single ADP-ribose unit to guanidine compounds, hydrolyses NAD in nicotinamide and free ADP-ribose, and ADP-ribosylates ...
Balducci, Enrico +1 more
core +1 more source
Frontiers in Microbiology, 2023 The recent discovery of the archaeal modified mevalonate pathway revealed that the fundamental units for isoprenoid biosynthesis (isopentenyl diphosphate and dimethylallyl diphosphate) are biosynthesized via a specific intermediate, trans ...
Mutsumi Komeyama +6 more
doaj +1 more source