Genomic Expansion of Magnetotactic Bacteria Reveals an Early Common Origin of Magnetotaxis with Lineage-specific Evolution [PDF]
, 2018 The origin and evolution of magnetoreception, which in diverse prokaryotes and protozoa is known as magnetotaxis and enables these microorganisms to detect Earth’s magnetic field for orientation and navigation, is not well understood in evolutionary ...
A Gurevich +67 more
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Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast
Redox Biology, 2018 Yeast frataxin homolog (Yfh1) is the orthologue of human frataxin, a mitochondrial protein whose deficiency causes Friedreich Ataxia. Yfh1 deficiency activates Aft1, a transcription factor governing iron homeostasis in yeast cells.
David Alsina, Joaquim Ros, Jordi Tamarit
doaj +1 more source
Frontiers in Microbiology, 2023 Microorganism-mediated biohydrometallurgy, a sustainable approach for metal recovery from ores, relies on the metabolic activity of acidophilic bacteria.
Liangzhi Li +12 more
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Microarray-based screening of differentially expressed genes of E. coli O157:H7 Sakai during preharvest survival on butterhead lettuce [PDF]
, 2016 Numerous outbreaks of Escherichia coli O157:H7 have been linked to the consumption of leafy vegetables. However, up to the present, little has been known about E.
Cottyn, Bart +6 more
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Molecules, 2018 Iron-sulfur (Fe-S) clusters, the ubiquitous protein cofactors found in all kingdoms of life, perform a myriad of functions including nitrogen fixation, ribosome assembly, DNA repair, mitochondrial respiration, and metabolite catabolism. The biogenesis of
Kai Cai, John L. Markley
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Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions. [PDF]
PLoS Biology, 2010 The cysteine desulfurase IscS is a highly conserved master enzyme initiating sulfur transfer via persulfide to a range of acceptor proteins involved in Fe-S cluster assembly, tRNA modifications, and sulfur-containing cofactor biosynthesis.
Rong Shi +8 more
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Redox-Sensing Iron–Sulfur Cluster Regulators [PDF]
, 2018 Significance: Iron–sulfur cluster proteins carry out multiple functions, including as regulators of gene transcription/translation in response to environmental stimuli.
Crack, Jason C, Le Brun, Nick E
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Maintenance of genome integrity by the late-acting cytoplasmic iron-sulfur assembly (CIA) complex
Frontiers in Genetics, 2023 Iron-sulfur (Fe-S) clusters are unique, redox-active co-factors ubiquitous throughout cellular metabolism. Fe-S cluster synthesis, trafficking, and coordination result from highly coordinated, evolutionarily conserved biosynthetic processes.
M. S. Petronek, B. G. Allen
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Human Frataxin Folds Via an Intermediate State. Role of the C-Terminal Region [PDF]
, 2016 The aim of this study is to investigate the folding reaction of human frataxin, whose deficiency causes the neurodegenerative disease Friedreich’s Ataxia (FRDA).
Faraj, Santiago Enrique +3 more
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Hsc66 substrate specificity is directed toward a discrete region of the iron-sulfur cluster template protein IscU [PDF]
, 2002 Hsc66 and Hsc20 comprise a specialized chaperone system important for the assembly of iron-sulfur clusters in Escherchia coli. Only a single substrate, the Fe/S template protein IscU, has been identified for the Hsc66/Hsc20 system, but the mechanism by ...
Hoff, Kevin G. +4 more
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