The in vitro activity of iron chelator deferiprone against Candida (Candidozyma) auris in combination with antifungal agents. [PDF]
Med MycolTóth Z +7 more
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From Microbes to Medicine: Targeting Metalloprotein Pathways for Innovative Antibacterial Strategies. [PDF]
Int J Mol SciAlshatari SS, Ziarno M.
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Heavy Metal Toxicity in Clinical and Environmental Health: Sources, Mechanisms, Diagnostics, and Evidence-Based Management of Mercury, Lead, Cadmium, and Arsenic. [PDF]
Int J Mol SciChakif D, Furrer J.
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Iron-Responsive Deferasirox Release from Covalently Grafted Hydrogels on Microwires Extends Iron Chelation Time Scales. [PDF]
ACS Appl Mater InterfacesMaleszka JA +10 more
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Iron chelating agents for the treatment of iron overload
Coordination Chemistry Reviews, 2008The importance of iron chelators in medicine has significantly increased in recent years. Iron is essential for life but it is also potentially more toxic than other trace elements. This is because we lack effective means to protect human cells against iron overload and because of the role of iron in the generation of free radicals. In order to protect
Guido Crisponi, Maurizio Remelli
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Iron chelating agents in clinical practice
Coordination Chemistry Reviews, 1999Abstract The relevance of iron chelators in medicine has increased in recent years. Iron is essential for life but it is also potentially more toxic than other trace elements. This is due to the lack of effective means to protect human cells against iron overload and to the role of iron in the generation of free radicals. To protect patients from the
Guido Crisponi
exaly +3 more sources
Silybin, a new iron-chelating agent
Journal of Inorganic Biochemistry, 2001Silybin, a natural occurring flavolignan isolated from the fruits of Silibum marianum, has been reported to exert antioxidant and free radical scavenging abilities. It was suggested to act also as an iron chelator. The complexation and protonation equilibria of the ferric complex of this compound have been studied by potentiometric, spectrophotometric ...
BORSARI, Marco +6 more
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Iron-Chelating Agents in Non-Iron Overload Conditions
Annals of Internal Medicine, 1994To review the current clinical experience with iron chelators in non-iron overload conditions.The English-language literature was searched from 1983 through 1992 manually and using MEDLINE.Original articles, case reports, and abstracts addressing iron chelation.Selected reports that described clinical applications of iron chelators in non-iron overload
E E, Voest, G, Vreugdenhil, J J, Marx
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Iron chelators as therapeutic iron depletion agents
Expert Opinion on Therapeutic Patents, 2006The great promise of iron depletion as a therapeutic strategy for various diseases, including iron overload, cancers, Alzheimer’s disease, Parkinson’s disease, tuberculosis, HIV, and fungal and malaria infection, has stimulated research on the development of iron chelators as iron depletion agents.
Noah Birch, Xiang Wang, Hyun-Soon Chong
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The Effect of Chelating Agents on Cellular Iron Metabolism
Clinical Science, 19761. The effect of iron chelators on iron uptake, ferritin and total protein synthesis was studied in cultured Chang cells. Desferrioxamine depressed ferritin synthesis and completely inhibited iron uptake by ferritin protein. Rhodotorulic acid reduced iron uptake by the cells but had little effect on ferritin synthesis.
G P, White, R, Bailey-Wood, A, Jacobs
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