Results 261 to 270 of about 20,621 (305)

Chelating agent differences in ferrous iron determinations

Journal of Plant Nutrition, 1984
Abstract Experiments were conducted to test the ability of ferrous iron (Fe2+) chelating agents to discriminate between Fe2+ and ferric iron (Fe3+), to determine ranges of Fe2+ detection in reactions, to determine interactions of chelating agents with phosphorus (P) which is common in plant tissue, and to evaluate some of the complexities of ...
E. E. Pierson, R. B. Clark
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Mobilization of ferritin iron in erythroblasts by chelating agents

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1985
Intracellular ferritin in newt (Triturus cristatus) erythroblasts was accessible to the chelating effects of EDTA and pyridoxal phosphate. EDTA (0.5-1 mM) promoted release of radioactive iron from ferritin of pulse-labelled erythroblasts during chase incubation, but its continuous presence was not necessary for ferritin iron mobilization.
J A, Grasso, T J, Hillis, J A, Mooney-Frank   +2 more
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The Effect of Chelating Agents on Cellular Iron Metabolism

Clinical Science, 1976
1. The effect of iron chelators on iron uptake, ferritin and total protein synthesis was studied in cultured Chang cells. Desferrioxamine depressed ferritin synthesis and completely inhibited iron uptake by ferritin protein. Rhodotorulic acid reduced iron uptake by the cells but had little effect on ferritin synthesis.
G P, White, R, Bailey-Wood, A, Jacobs
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Chelating Agents for the Treatment of Systemic Iron Overload

Current Medicinal Chemistry, 2012
The first successful therapeutic iron chelator was desferrioxamine which was introduced in the late 1960's by Ciba (now Novartis). Desferrioxamine has been an extremely successful compound having received the MMW "Pharmaceutical of the year" award for 1991. It is a life saving and a life - prolonging drug which improves the quality of life.
Ma, Yongmin, Zhou, T., Kong, X., Hider, R. C.   +3 more
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Cell Permeable Iron Chelators as Potential Cancer Chemotherapeutic Agents

Cancer Investigation, 2005
Iron is an essential micronutrient for the growth and function of all cells. It is, therefore, an attractive target for chemotherapeutic compounds. Numerous studies in vitro and in vivo provide evidence that iron chelators may be effective antitumor agents. Lipophilic iron chelators that are readily cell permeable and can bind intracellular iron stores
Paula M B, Pahl, Lawrence D, Horwitz
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EFFECT OF AN IRON‐CHELATING AGENT ON LYMPHOCYTE PROLIFERATION

Australian Journal of Experimental Biology and Medical Science, 1984
SummaryThe effect of the iron‐chelating: agent desferrioxamine on lymphocyte proliferation has been studied. Desferrioxamine at concentrations of 15 μM totally inhibited the proliferation of Concanavalin A‐stimulated lymphocytes, whereas iron‐saturated desferrioxamine was ineffective.
N, Bowern, I A, Ramshaw, P, Badenoch-Jones, P C, Doherty   +3 more
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Potential of iron chelators as effective antiproliferative agents

Canadian Journal of Physiology and Pharmacology, 1997
Initially the impetus to develop iron (Fe) chelators for clinical use was based upon the need for a drug to treat Fe-overload diseases such as beta-thalassemia. However, it has become clear that Fe chelators may be useful for the treatment of a wide variety of disease states, including cancer, malaria, and free radical mediated injury.
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Interaction of Iron Chelating Agents with Clay Minerals

Soil Science Society of America Journal, 2004
Organic ligands play an important role in metal transport and availability in soils. However, their interaction with the solid phase of soils has not been sufficiently investigated. Two efficient Fe chelators were investigated in this study, as free ligands as well as Fe complexes: (i) the microbial siderophore ferrioxamine B ...
H. Siebner-Freibach, Y. Hadar, Y. Chen
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ChemInform Abstract: Iron Chelating Agents in Clinical Practice

ChemInform, 1999
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Gavino Faa, Guido Crisponi
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The Behaviour of Iron Chelating Agents with Plants

Journal of Experimental Botany, 1965
The absorption by normal and iron-deficient bean plants of Fe and of ethylene diamine-bis-(orthohydroxyphenylacetic acid) (EDHPA) is described; and the metabolism in plants of this chelating agent and of ethylenediaminetetra-acetic acid (EDTA) is examined using 14C-labelled compounds.
D. G. HILL-COTTINGHAM, C. P. LLOYD-JONES
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