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Iron Overload, Clonal Hematopoiesis, and Cancer Risk in Aging and Transfusion-Dependent Populations: A Literature Review. [PDF]
CureusLa QD +11 more
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Organic ligands and CO<sub>2</sub> unlock the potential for energy relevant metals recovery and carbon mineralization from mafic rocks. [PDF]
Sci RepKatre S +6 more
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ChemInform Abstract: Iron Chelating Agents in Clinical Practice [PDF]
ChemInform, 1999 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
CRISPONI, GUIDO, FAA, GAVINO
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Iron chelating agents for the treatment of iron overload
Coordination Chemistry Reviews, 2008The importance of iron chelators in medicine has significantly increased in recent years. Iron is essential for life but it is also potentially more toxic than other trace elements. This is because we lack effective means to protect human cells against iron overload and because of the role of iron in the generation of free radicals. In order to protect
G. CRISPONI, REMELLI, Maurizio
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Silybin, a new iron-chelating agent
Journal of Inorganic Biochemistry, 2001Silybin, a natural occurring flavolignan isolated from the fruits of Silibum marianum, has been reported to exert antioxidant and free radical scavenging abilities. It was suggested to act also as an iron chelator. The complexation and protonation equilibria of the ferric complex of this compound have been studied by potentiometric, spectrophotometric ...
BORSARI, Marco +6 more
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The Effect of Chelating Agents on Cellular Iron Metabolism [PDF]
Clinical Science, 1976 1. The effect of iron chelators on iron uptake, ferritin and total protein synthesis was studied in cultured Chang cells. Desferrioxamine depressed ferritin synthesis and completely inhibited iron uptake by ferritin protein. Rhodotorulic acid reduced iron uptake by the cells but had little effect on ferritin synthesis.
R. Bailey-Wood, A. Jacobs, G. P. White
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Iron chelators as therapeutic iron depletion agents
Expert Opinion on Therapeutic Patents, 2006The great promise of iron depletion as a therapeutic strategy for various diseases, including iron overload, cancers, Alzheimer’s disease, Parkinson’s disease, tuberculosis, HIV, and fungal and malaria infection, has stimulated research on the development of iron chelators as iron depletion agents.
Noah Birch, Hyun-Soon Chong, Xiang Wang
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Iron-Chelating Agents in Non-Iron Overload Conditions
Annals of Internal Medicine, 1994To review the current clinical experience with iron chelators in non-iron overload conditions.The English-language literature was searched from 1983 through 1992 manually and using MEDLINE.Original articles, case reports, and abstracts addressing iron chelation.Selected reports that described clinical applications of iron chelators in non-iron overload
G. Vreugdenhil +2 more
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Antioxidant and Iron-chelating Agents in Cerebral Vasospasm
Neurosurgery, 1995Prior work in our laboratory showed that the perivascular application of deferoxamine (an antioxidant and iron-chelating agent) inhibited delayed arterial narrowing after chronic blood exposure in a rat femoral artery model of vasospasm. To determine which of these mechanisms was operant in vasospasm, we compared deferoxamine with two agents (ascorbic ...
Tsutomu Harada +4 more
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